Detailed information NTG1041222

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACDZ05_RS12970
• Genome accession: NZ_CP168013
• Coordinates: 2622120..2623007 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain sa230711_barcode73
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2617120..2628007

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACDZ05_RS12940 (ACDZ05_12945)	-	2617129..2617221 (+)	93	WP_031774855.1	hypothetical protein	-
ACDZ05_RS12945 (ACDZ05_12950)	-	2617329..2617826 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACDZ05_RS12950 (ACDZ05_12955)	-	2617836..2618096 (-)	261	WP_014937088.1	hypothetical protein	-
ACDZ05_RS12955 (ACDZ05_12960)	-	2618478..2618591 (-)	114	WP_014937089.1	hypothetical protein	-
ACDZ05_RS12960 (ACDZ05_12965)	-	2619260..2621260 (-)	2001	WP_000776741.1	ABC transporter permease	-
ACDZ05_RS12965 (ACDZ05_12970)	-	2621257..2622012 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACDZ05_RS12970 (ACDZ05_12975)	braS	2622120..2623007 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACDZ05_RS12975 (ACDZ05_12980)	braR	2623018..2623683 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACDZ05_RS12980 (ACDZ05_12985)	-	2623709..2623909 (-)	201	WP_000604731.1	hypothetical protein	-
ACDZ05_RS12985 (ACDZ05_12990)	-	2624107..2625531 (+)	1425	WP_000953736.1	alkaline phosphatase	-
ACDZ05_RS12990 (ACDZ05_12995)	-	2625591..2625692 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACDZ05_RS12995 (ACDZ05_13000)	-	2625814..2626269 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACDZ05_RS13000 (ACDZ05_13005)	-	2626513..2627274 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1041222 ACDZ05_RS12970 WP_000143420.1 2622120..2623007(-) (braS) [Staphylococcus aureus strain sa230711_barcode73]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1041222 ACDZ05_RS12970 WP_000143420.1 2622120..2623007(-) (braS) [Staphylococcus aureus strain sa230711_barcode73]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993