Detailed information NTG1041003

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: KJP47_RS00590
• Genome accession: NZ_OX419577
• Coordinates: 108711..109793 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis isolate NRS6120
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 103711..114793

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJP47_RS00575 (NRS6120_00625)	mcsB	103719..104810 (+)	1092	WP_003235007.1	protein arginine kinase	-
KJP47_RS00580 (NRS6120_00630)	clpC	104807..107239 (+)	2433	WP_213383247.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
KJP47_RS00585 (NRS6120_00635)	radA/sms	107331..108707 (+)	1377	WP_213383246.1	DNA repair protein RadA	Machinery gene
KJP47_RS00590 (NRS6120_00640)	disA	108711..109793 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
KJP47_RS00595 (NRS6120_00645)	yacL	109909..111009 (+)	1101	WP_043858286.1	PIN/TRAM domain-containing protein	-
KJP47_RS00600 (NRS6120_00650)	ispD	111024..111722 (+)	699	WP_213383245.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
KJP47_RS00605 (NRS6120_00655)	ispF	111715..112191 (+)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
KJP47_RS00610 (NRS6120_00660)	gltX	112282..113733 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
KJP47_RS00615 (NRS6120_00665)	cysE	114035..114688 (+)	654	WP_213383244.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=1041003 KJP47_RS00590 WP_003225736.1 108711..109793(+) (disA) [Bacillus subtilis isolate NRS6120]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=1041003 KJP47_RS00590 WP_003225736.1 108711..109793(+) (disA) [Bacillus subtilis isolate NRS6120]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGCTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCTGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCAGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTGATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCAAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAAGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1