Detailed information NTG1040913

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK31_RS13990
• Genome accession: NZ_CP167987
• Coordinates: 2774407..2775294 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-14
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2769407..2780294

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK31_RS13960 (ACCK31_13960)	-	2769426..2769518 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK31_RS13965 (ACCK31_13965)	-	2769626..2770123 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK31_RS13970 (ACCK31_13970)	-	2770133..2770393 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK31_RS13975 (ACCK31_13975)	-	2770775..2770888 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK31_RS13980 (ACCK31_13980)	-	2771547..2773547 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK31_RS13985 (ACCK31_13985)	-	2773544..2774299 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK31_RS13990 (ACCK31_13990)	braS	2774407..2775294 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK31_RS13995 (ACCK31_13995)	braR	2775305..2775970 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK31_RS14000 (ACCK31_14000)	-	2775996..2776196 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK31_RS14005 (ACCK31_14005)	-	2776394..2777818 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK31_RS14010 (ACCK31_14010)	-	2777878..2777979 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK31_RS14015 (ACCK31_14015)	-	2778101..2778556 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK31_RS14020 (ACCK31_14020)	-	2778801..2779562 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1040913 ACCK31_RS13990 WP_000143419.1 2774407..2775294(-) (braS) [Staphylococcus aureus strain CUBIST-14]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1040913 ACCK31_RS13990 WP_000143419.1 2774407..2775294(-) (braS) [Staphylococcus aureus strain CUBIST-14]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997