Detailed information NTG1040458

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK29_RS14345
• Genome accession: NZ_CP167940
• Coordinates: 2818390..2819277 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-31
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2813390..2824277

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK29_RS14315 (ACCK29_14315)	-	2813409..2813501 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK29_RS14320 (ACCK29_14320)	-	2813609..2814106 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK29_RS14325 (ACCK29_14325)	-	2814116..2814376 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK29_RS14330 (ACCK29_14330)	-	2814758..2814871 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK29_RS14335 (ACCK29_14335)	-	2815530..2817530 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK29_RS14340 (ACCK29_14340)	-	2817527..2818282 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK29_RS14345 (ACCK29_14345)	braS	2818390..2819277 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK29_RS14350 (ACCK29_14350)	braR	2819288..2819953 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK29_RS14355 (ACCK29_14355)	-	2819979..2820179 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK29_RS14360 (ACCK29_14360)	-	2820377..2821801 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK29_RS14365 (ACCK29_14365)	-	2821861..2821962 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK29_RS14370 (ACCK29_14370)	-	2822084..2822539 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK29_RS14375 (ACCK29_14375)	-	2822784..2823545 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1040458 ACCK29_RS14345 WP_000143419.1 2818390..2819277(-) (braS) [Staphylococcus aureus strain CUBIST-31]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1040458 ACCK29_RS14345 WP_000143419.1 2818390..2819277(-) (braS) [Staphylococcus aureus strain CUBIST-31]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997