Detailed information NTG1040416

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK23_RS13970
• Genome accession: NZ_CP167937
• Coordinates: 2768445..2769332 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-35
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2763445..2774332

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK23_RS13940 (ACCK23_13940)	-	2763464..2763556 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK23_RS13945 (ACCK23_13945)	-	2763664..2764161 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK23_RS13950 (ACCK23_13950)	-	2764171..2764431 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK23_RS13955 (ACCK23_13955)	-	2764813..2764926 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK23_RS13960 (ACCK23_13960)	-	2765585..2767585 (-)	2001	WP_372420894.1	FtsX-like permease family protein	-
ACCK23_RS13965 (ACCK23_13965)	-	2767582..2768337 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK23_RS13970 (ACCK23_13970)	braS	2768445..2769332 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK23_RS13975 (ACCK23_13975)	braR	2769343..2770008 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK23_RS13980 (ACCK23_13980)	-	2770034..2770234 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK23_RS13985 (ACCK23_13985)	-	2770432..2771856 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK23_RS13990 (ACCK23_13990)	-	2771916..2772017 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK23_RS13995 (ACCK23_13995)	-	2772139..2772594 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK23_RS14000 (ACCK23_14000)	-	2772839..2773600 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1040416 ACCK23_RS13970 WP_000143419.1 2768445..2769332(-) (braS) [Staphylococcus aureus strain CUBIST-35]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1040416 ACCK23_RS13970 WP_000143419.1 2768445..2769332(-) (braS) [Staphylococcus aureus strain CUBIST-35]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997