Detailed information NTG1040333

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK30_RS14320
• Genome accession: NZ_CP167931
• Coordinates: 2819186..2820073 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-43
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2814186..2825073

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK30_RS14290 (ACCK30_14290)	-	2814205..2814297 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK30_RS14295 (ACCK30_14295)	-	2814405..2814902 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK30_RS14300 (ACCK30_14300)	-	2814912..2815172 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK30_RS14305 (ACCK30_14305)	-	2815554..2815667 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK30_RS14310 (ACCK30_14310)	-	2816326..2818326 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK30_RS14315 (ACCK30_14315)	-	2818323..2819078 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK30_RS14320 (ACCK30_14320)	braS	2819186..2820073 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK30_RS14325 (ACCK30_14325)	braR	2820084..2820749 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK30_RS14330 (ACCK30_14330)	-	2820775..2820975 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK30_RS14335 (ACCK30_14335)	-	2821173..2822597 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK30_RS14340 (ACCK30_14340)	-	2822657..2822758 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK30_RS14345 (ACCK30_14345)	-	2822880..2823335 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK30_RS14350 (ACCK30_14350)	-	2823580..2824341 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1040333 ACCK30_RS14320 WP_000143419.1 2819186..2820073(-) (braS) [Staphylococcus aureus strain CUBIST-43]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1040333 ACCK30_RS14320 WP_000143419.1 2819186..2820073(-) (braS) [Staphylococcus aureus strain CUBIST-43]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997