Detailed information NTG1040269

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: CWH_RS21010
• Genome accession: NZ_CP167924
• Coordinates: 4008753..4009547 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain CWH_147
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4003753..4014547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWH_RS20990	-	4005554..4005787 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
CWH_RS20995	-	4005836..4006564 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
CWH_RS21000	-	4006615..4006761 (+)	147	WP_001247671.1	YycC family protein	-
CWH_RS21005	-	4006929..4008455 (-)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
CWH_RS21010	spo0A	4008753..4009547 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
CWH_RS21015	spoIVB	4009835..4011133 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
CWH_RS21020	recN	4011252..4012991 (-)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
CWH_RS21025	argR	4013259..4013708 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=1040269 CWH_RS21010 WP_003161566.1 4008753..4009547(-) (spo0A) [Bacillus anthracis strain CWH_147]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=1040269 CWH_RS21010 WP_003161566.1 4008753..4009547(-) (spo0A) [Bacillus anthracis strain CWH_147]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818