Detailed information NTG1039914

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: KJP64_RS00585
• Genome accession: NZ_OX419565
• Coordinates: 106991..108073 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis isolate NRS6145
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 101991..113073

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJP64_RS00570 (NRS6145_00580)	mcsB	101999..103090 (+)	1092	WP_003235007.1	protein arginine kinase	-
KJP64_RS00575 (NRS6145_00585)	clpC	103087..105519 (+)	2433	WP_003235011.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
KJP64_RS00580 (NRS6145_00590)	radA/sms	105611..106987 (+)	1377	WP_004399687.1	DNA repair protein RadA	Machinery gene
KJP64_RS00585 (NRS6145_00595)	disA	106991..108073 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
KJP64_RS00590 (NRS6145_00600)	yacL	108189..109289 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
KJP64_RS00595 (NRS6145_00605)	ispD	109304..110002 (+)	699	WP_003235019.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
KJP64_RS00600 (NRS6145_00610)	ispF	109995..110471 (+)	477	WP_003225745.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
KJP64_RS00605 (NRS6145_00615)	gltX	110562..112013 (+)	1452	WP_004399675.1	glutamate--tRNA ligase	-
KJP64_RS00610 (NRS6145_00620)	cysE	112315..112968 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=1039914 KJP64_RS00585 WP_003225736.1 106991..108073(+) (disA) [Bacillus subtilis isolate NRS6145]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=1039914 KJP64_RS00585 WP_003225736.1 106991..108073(+) (disA) [Bacillus subtilis isolate NRS6145]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TAGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGCTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCTGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAATATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTCCTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGACATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCTGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAGGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1