Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACCO40_RS06255 Genome accession   NZ_CP167793
Coordinates   1230567..1231223 (+) Length   218 a.a.
NCBI ID   WP_014113374.1    Uniprot ID   G4NWF3
Organism   Bacillus spizizenii strain SHT-15     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1225567..1236223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACCO40_RS06225 (ACCO40_06225) oppF 1225812..1226729 (+) 918 WP_114150709.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACCO40_RS06230 (ACCO40_06230) - 1226835..1228049 (+) 1215 WP_372402787.1 MFS transporter -
  ACCO40_RS06235 (ACCO40_06235) - 1228226..1228804 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ACCO40_RS06240 (ACCO40_06240) spx 1228985..1229380 (+) 396 WP_003239281.1 transcriptional regulator Spx -
  ACCO40_RS06245 (ACCO40_06245) - 1229635..1230291 (-) 657 WP_003224601.1 TerC family protein -
  ACCO40_RS06250 (ACCO40_06250) - 1230475..1230600 (+) 126 WP_120698858.1 hypothetical protein -
  ACCO40_RS06255 (ACCO40_06255) mecA 1230567..1231223 (+) 657 WP_014113374.1 adaptor protein MecA Regulator
  ACCO40_RS06260 (ACCO40_06260) - 1231218..1231340 (-) 123 Protein_1168 hypothetical protein -
  ACCO40_RS06265 (ACCO40_06265) coiA 1231384..1232535 (+) 1152 WP_087988072.1 competence protein CoiA family protein Machinery gene
  ACCO40_RS06270 (ACCO40_06270) pepF 1232765..1234594 (+) 1830 WP_176364382.1 oligoendopeptidase F -
  ACCO40_RS06275 (ACCO40_06275) - 1234632..1234799 (-) 168 WP_041520918.1 hypothetical protein -
  ACCO40_RS06280 (ACCO40_06280) spxH 1235113..1236012 (-) 900 WP_072566099.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25730.60 Da        Isoelectric Point: 4.1174

>NTDB_id=1039405 ACCO40_RS06255 WP_014113374.1 1230567..1231223(+) (mecA) [Bacillus spizizenii strain SHT-15]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFGNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1039405 ACCO40_RS06255 WP_014113374.1 1230567..1231223(+) (mecA) [Bacillus spizizenii strain SHT-15]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAGGAAGAGGAAT
TTGCTGTGGAAGGCCCTCTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATTGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGGTTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTGGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTGGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G4NWF3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment