Detailed information NTG1039247

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK20_RS14020
• Genome accession: NZ_CP167765
• Coordinates: 2768398..2769285 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-47
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2763398..2774285

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK20_RS13990 (ACCK20_13990)	-	2763417..2763509 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK20_RS13995 (ACCK20_13995)	-	2763617..2764114 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK20_RS14000 (ACCK20_14000)	-	2764124..2764384 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK20_RS14005 (ACCK20_14005)	-	2764766..2764879 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK20_RS14010 (ACCK20_14010)	-	2765538..2767538 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK20_RS14015 (ACCK20_14015)	-	2767535..2768290 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK20_RS14020 (ACCK20_14020)	braS	2768398..2769285 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK20_RS14025 (ACCK20_14025)	braR	2769296..2769961 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK20_RS14030 (ACCK20_14030)	-	2769987..2770187 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK20_RS14035 (ACCK20_14035)	-	2770385..2771809 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK20_RS14040 (ACCK20_14040)	-	2771869..2771970 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK20_RS14045 (ACCK20_14045)	-	2772092..2772547 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK20_RS14050 (ACCK20_14050)	-	2772792..2773553 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1039247 ACCK20_RS14020 WP_000143419.1 2768398..2769285(-) (braS) [Staphylococcus aureus strain CUBIST-47]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1039247 ACCK20_RS14020 WP_000143419.1 2768398..2769285(-) (braS) [Staphylococcus aureus strain CUBIST-47]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997