Detailed information NTG1039205

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK13_RS13730
• Genome accession: NZ_CP167764
• Coordinates: 2715112..2715999 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CUBIST-10
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2710112..2720999

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK13_RS13700 (ACCK13_13700)	-	2710131..2710223 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK13_RS13705 (ACCK13_13705)	-	2710331..2710828 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK13_RS13710 (ACCK13_13710)	-	2710838..2711098 (-)	261	WP_001791974.1	hypothetical protein	-
ACCK13_RS13715 (ACCK13_13715)	-	2711480..2711593 (-)	114	Protein_2633	hypothetical protein	-
ACCK13_RS13720 (ACCK13_13720)	-	2712252..2714252 (-)	2001	WP_000776750.1	ABC transporter permease	-
ACCK13_RS13725 (ACCK13_13725)	-	2714249..2715004 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK13_RS13730 (ACCK13_13730)	braS	2715112..2715999 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK13_RS13735 (ACCK13_13735)	braR	2716010..2716675 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK13_RS13740 (ACCK13_13740)	-	2716701..2716901 (-)	201	WP_000604730.1	hypothetical protein	-
ACCK13_RS13745 (ACCK13_13745)	-	2717099..2718523 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ACCK13_RS13750 (ACCK13_13750)	-	2718583..2718684 (-)	102	WP_000731976.1	SE2200 family small protein	-
ACCK13_RS13755 (ACCK13_13755)	-	2718806..2719261 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK13_RS13760 (ACCK13_13760)	-	2719506..2720267 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1039205 ACCK13_RS13730 WP_000143425.1 2715112..2715999(-) (braS) [Staphylococcus aureus strain CUBIST-10]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1039205 ACCK13_RS13730 WP_000143425.1 2715112..2715999(-) (braS) [Staphylococcus aureus strain CUBIST-10]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1