Detailed information NTG1037867

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ACB327_RS05680
• Genome accession: NZ_CP167020
• Coordinates: 1133770..1136049 (+)
• Length: 759 a.a.
• NCBI ID: WP_371400055.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 6
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1128770..1141049

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB327_RS05660 (ACB327_05660)	-	1130137..1131546 (-)	1410	WP_023610117.1	deoxyribodipyrimidine photo-lyase	-
ACB327_RS05665 (ACB327_05665)	-	1131695..1132429 (-)	735	WP_010922488.1	amino acid ABC transporter ATP-binding protein	-
ACB327_RS05670 (ACB327_05670)	-	1132429..1133115 (-)	687	WP_011054708.1	amino acid ABC transporter permease	-
ACB327_RS05675 (ACB327_05675)	-	1133242..1133472 (-)	231	WP_002983885.1	YkuJ family protein	-
ACB327_RS05680 (ACB327_05680)	clpE	1133770..1136049 (+)	2280	WP_371400055.1	AAA family ATPase	Regulator
ACB327_RS05685 (ACB327_05685)	-	1136177..1136632 (+)	456	WP_020905319.1	NUDIX hydrolase	-
ACB327_RS05690 (ACB327_05690)	-	1136683..1136985 (+)	303	WP_002983878.1	DUF1827 family protein	-
ACB327_RS05695 (ACB327_05695)	ileS	1137249..1140050 (-)	2802	WP_076639311.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 759 a.a.
• Molecular weight: 84575.73 Da
• Isoelectric Point: 5.0552

>NTDB_id=1037867 ACB327_RS05680 WP_371400055.1 1133770..1136049(+) (clpE) [Streptococcus pyogenes strain Isolate 6]
MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSILNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRYGGNYNGQRPAQPQTPNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
ITKYKEMQAQKAEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGLG
TPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYS
LILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFSP
EFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITD
YYLEHPTEKQLRALMTNSENITIKAVKEGDSFLNEESLD

Nucleotide

• Length: 2280 bp

>NTDB_id=1037867 ACB327_RS05680 WP_371400055.1 1133770..1136049(+) (clpE) [Streptococcus pyogenes strain Isolate 6]
ATGCTGTGTCAAAATTGTAATTTAAACGAATCTACTATTCATCTTTATACAAGTGTTAATGGAAAACAAAGACAGGTTGA
TCTCTGTCAAAATTGTTATCAAATCATGAAATCCGATCCTGCCAATTCTATTTTAAATGGCCTAACCCCAGGATATAGAG
CACAAGATAGATCCACAAGTCCTTTCTTTGATGACTTTTTTGGTGATTTGAATAATTTTAGAGCTTTTGGTAATCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGCGGAGGACGCTATGGTGGTAACTACAACGGACAACGACCTGC
TCAGCCACAAACACCAAATCAGCAAGCAAAGGGCTTATTAGAAGAGTTTGGGATTAATGTCACAGATATTGCAAGAAATG
GTAATATTGATCCTGTTATTGGTCGTGACGAAGAGATTACACGCGTTATCGAGATCCTCAACCGCCGTACTAAAAATAAT
CCTGTGCTAATTGGTGAGCCTGGAGTTGGTAAAACTGCTGTTGTAGAAGGTTTGGCTCAAAAAATTATTGATGGTACTGT
TCCTCAAAAACTCCAAGGCAAGCAAGTGATTCGTCTTGATGTGGTTAGCCTCGTTCAGGGAACAGGTATCCGTGGTCAGT
TTGAAGAGCGCATGCAAAAATTAATGGAAGAAATTCGCAATCGCAAGGATGTGATTCTCTTTATTGATGAAATTCATGAG
ATTGTCGGTGCTGGTTCTGCAGGAGACGGCAATATGGATGCTGGTAATATTTTAAAACCAGCCTTGGCCCGCGGTGAATT
GCAGTTGGTCGGCGCTACCACCTTAAATGAATATCGTATTATTGAAAAAGACGCTGCCTTAGAACGACGTATGCAACCCG
TTAAAGTTGATGAACCTTCTGTTGAGGAAACCATCACGATTTTAAAAGGTATCCAACCGAAATACGAAGACTATCATCAT
GTCAAATATAGCCCAGCCGCTATTGAAGCTGCCGCTCATTTATCTAACCGCTATATTCAAGACCGTTTTCTTCCTGATAA
GGCTATTGACCTTCTGGACGAAGCTGGTTCCAAAATGAATCTAACCCTCAACTTTGTTGATCCTAAAGAAATTGACAAAC
GTCTTATTGAAGCTGAGAATCTCAAGGCGCAAGCTACTCGAGACGAAGACTATGAACGCGCAGCTTATTTCCGCGATCAA
ATTACAAAATACAAAGAAATGCAGGCTCAAAAAGCTGAGCAAGATATTCCCATCATTACTGAAAAAACCATTGAAGCTAT
TGTAGAGCAAAAAACTAATATTCCAGTTGGGGACTTAAAAGAAAAGGAACAGTCTCAACTCGTAAACTTAGCCAATGATC
TGAAAGCACACGTGATCGGGCAAGACGATGCTGTTGATAAAATCGCTAAGGCTATTCGTCGTAACCGTGTGGGATTAGGA
ACTCCAAATCGCCCTATTGGTTCTTTCCTATTCGTTGGACCGACTGGGGTTGGTAAAACAGAATTGTCTAAACAACTAGC
CATTGAACTCTTTGGTTCGACAAACAATATGATTCGCTTTGACATGTCCGAATACATGGAAAAACACGCTGTTGCCAAAT
TAGTCGGGGCTCCTCCAGGTTATGTCGGCTATGAAGAAGCTGGACAGCTAACCGAACAAGTTCGTCGCAATCCATATTCA
CTTATTCTCTTAGATGAGGTGGAAAAGGCTCATCCTGACGTCATGCACATGTTCTTACAAGTTCTTGATGACGGTCGCTT
AACAGACGGTCAAGGGCGAACAGTCAGCTTCAAGGACACCATTATTATCATGACCTCTAATGCCGGAACAGGTAAAAGCG
AAGCTTCTGTCGGATTTGGTGCTGCTAGAGAAGGACGGACAAGTTCTGTCCTTGGTGAATTAAGCAACTTCTTCAGCCCA
GAGTTTATGAATCGTTTCGATGGTATTATTGAATTCAAAGCTTTATCTAAAGAACATTTGCTGCATATCGTTGATTTAAT
GCTGGAAGATGTTAATGAGCGCTTAGGCTATAATGGGATTCATCTTGATGTGACACAAAAGGTCAAAGAAAAATTAGTAG
ATTTAGGCTATGATCCTAAAATGGGCGCTCGGCCGCTCCGTCGTACTATCCAAGATTATATCGAAGATGCCATTACAGAC
TATTATTTAGAACACCCAACTGAAAAACAGTTACGTGCACTGATGACAAACAGTGAAAACATCACGATTAAAGCTGTTAA
AGAGGGAGATTCTTTTCTTAACGAAGAGTCTCTAGATTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (484-647)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (655-728)

• AAA lid domain (AAA_lid_9) (300-397)

• ATPase family associated with various cellular activities (AAA) (AAA) (162-281)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.626	98.551	0.834
clpE	Streptococcus pneumoniae Rx1	82.69	98.946	0.818
clpE	Streptococcus pneumoniae D39	82.69	98.946	0.818
clpE	Streptococcus pneumoniae R6	82.69	98.946	0.818
clpE	Streptococcus pneumoniae TIGR4	82.557	98.946	0.817
clpC	Lactococcus lactis subsp. cremoris KW2	75.033	100	0.752
clpC	Bacillus subtilis subsp. subtilis str. 168	51.529	86.166	0.444
clpC	Streptococcus pneumoniae D39	47.917	82.213	0.394
clpC	Streptococcus pneumoniae Rx1	47.917	82.213	0.394
clpC	Streptococcus pneumoniae TIGR4	47.917	82.213	0.394
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.917	85.507	0.393
clpC	Streptococcus mutans UA159	47.812	81.291	0.389
clpC	Streptococcus thermophilus LMD-9	47.03	82.082	0.386
clpC	Streptococcus thermophilus LMG 18311	46.709	82.082	0.383