Detailed information NTG1037592

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ACB351_RS06080
• Genome accession: NZ_CP167015
• Coordinates: 1209912..1210949 (-)
• Length: 345 a.a.
• NCBI ID: WP_011284961.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 11
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1204912..1215949

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB351_RS06055 (ACB351_06055)	-	1204925..1205452 (-)	528	WP_002983837.1	Dps family protein	-
ACB351_RS06060 (ACB351_06060)	-	1205680..1206306 (+)	627	WP_002983834.1	A24 family peptidase	-
ACB351_RS06065 (ACB351_06065)	rlmN	1206388..1207448 (-)	1061	Protein_1150	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
ACB351_RS06070 (ACB351_06070)	-	1207452..1208072 (-)	621	WP_002992791.1	YutD family protein	-
ACB351_RS06075 (ACB351_06075)	-	1208520..1209497 (-)	978	WP_021341005.1	LacI family DNA-binding transcriptional regulator	-
ACB351_RS06080 (ACB351_06080)	sepM	1209912..1210949 (-)	1038	WP_011284961.1	SepM family pheromone-processing serine protease	Regulator
ACB351_RS06085 (ACB351_06085)	coaD	1210936..1211427 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
ACB351_RS06090 (ACB351_06090)	rsmD	1211417..1211956 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACB351_RS06095 (ACB351_06095)	asnA	1212079..1213071 (-)	993	WP_002983817.1	aspartate--ammonia ligase	-
ACB351_RS06100 (ACB351_06100)	arcC	1213384..1214334 (-)	951	WP_009880962.1	carbamate kinase	-
ACB351_RS06105 (ACB351_06105)	-	1214354..1215685 (-)	1332	WP_011284962.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=1037592 ACB351_RS06080 WP_011284961.1 1209912..1210949(-) (sepM) [Streptococcus pyogenes strain Isolate 11]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDTDFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1037592 ACB351_RS06080 WP_011284961.1 1209912..1210949(-) (sepM) [Streptococcus pyogenes strain Isolate 11]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATACTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69