Detailed information NTG1037578

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACB351_RS02245
• Genome accession: NZ_CP167015
• Coordinates: 417765..418766 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Isolate 11
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 412765..423766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB351_RS02220 (ACB351_02220)	-	413439..414122 (-)	684	WP_011017476.1	DUF969 domain-containing protein	-
ACB351_RS02225 (ACB351_02225)	-	414333..415259 (-)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
ACB351_RS02230 (ACB351_02230)	-	415404..415781 (-)	378	WP_002985686.1	VOC family protein	-
ACB351_RS02235 (ACB351_02235)	-	415792..416457 (-)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
ACB351_RS02240 (ACB351_02240)	-	416506..417591 (-)	1086	WP_011284589.1	aminopeptidase P family protein	-
ACB351_RS02245 (ACB351_02245)	ccpA	417765..418766 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ACB351_RS02250 (ACB351_02250)	-	418897..419895 (+)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
ACB351_RS02255 (ACB351_02255)	-	419897..421231 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
ACB351_RS02260 (ACB351_02260)	thrS	421653..423596 (+)	1944	WP_011284591.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1037578 ACB351_RS02245 WP_002985680.1 417765..418766(+) (ccpA) [Streptococcus pyogenes strain Isolate 11]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1037578 ACB351_RS02245 WP_002985680.1 417765..418766(+) (ccpA) [Streptococcus pyogenes strain Isolate 11]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559