Detailed information NTG1037526

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACB359_RS02270
• Genome accession: NZ_CP167013
• Coordinates: 423627..424628 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Isolate 16
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 418627..429628

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB359_RS02245 (ACB359_02245)	-	419301..419984 (-)	684	WP_031488436.1	DUF969 domain-containing protein	-
ACB359_RS02250 (ACB359_02250)	-	420195..421121 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ACB359_RS02255 (ACB359_02255)	-	421266..421643 (-)	378	WP_002985686.1	VOC family protein	-
ACB359_RS02260 (ACB359_02260)	-	421654..422319 (-)	666	WP_031488435.1	NAD(P)H-dependent oxidoreductase	-
ACB359_RS02265 (ACB359_02265)	-	422368..423453 (-)	1086	WP_031488434.1	aminopeptidase P family protein	-
ACB359_RS02270 (ACB359_02270)	ccpA	423627..424628 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ACB359_RS02275 (ACB359_02275)	-	424759..425757 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ACB359_RS02280 (ACB359_02280)	-	425759..427093 (+)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
ACB359_RS02285 (ACB359_02285)	thrS	427515..429458 (+)	1944	WP_002985672.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1037526 ACB359_RS02270 WP_002985680.1 423627..424628(+) (ccpA) [Streptococcus pyogenes strain Isolate 16]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1037526 ACB359_RS02270 WP_002985680.1 423627..424628(+) (ccpA) [Streptococcus pyogenes strain Isolate 16]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGGTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559