Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   ACB352_RS03505 Genome accession   NZ_CP167009
Coordinates   666028..667065 (+) Length   345 a.a.
NCBI ID   WP_011284961.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 22     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 661028..672065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB352_RS03480 (ACB352_03480) - 661292..662623 (+) 1332 WP_011284962.1 dipeptidase -
  ACB352_RS03485 (ACB352_03485) arcC 662643..663593 (+) 951 WP_009880962.1 carbamate kinase -
  ACB352_RS03490 (ACB352_03490) asnA 663906..664898 (+) 993 WP_002983817.1 aspartate--ammonia ligase -
  ACB352_RS03495 (ACB352_03495) rsmD 665021..665560 (+) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ACB352_RS03500 (ACB352_03500) coaD 665550..666041 (+) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  ACB352_RS03505 (ACB352_03505) sepM 666028..667065 (+) 1038 WP_011284961.1 SepM family pheromone-processing serine protease Regulator
  ACB352_RS03510 (ACB352_03510) - 667480..668457 (+) 978 WP_021341005.1 LacI family DNA-binding transcriptional regulator -
  ACB352_RS03515 (ACB352_03515) - 668905..669525 (+) 621 WP_002992791.1 YutD family protein -
  ACB352_RS03520 (ACB352_03520) rlmN 669529..670608 (+) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  ACB352_RS03525 (ACB352_03525) - 670690..671316 (-) 627 WP_002983834.1 A24 family peptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37571.27 Da        Isoelectric Point: 9.6692

>NTDB_id=1037311 ACB352_RS03505 WP_011284961.1 666028..667065(+) (sepM) [Streptococcus pyogenes strain Isolate 22]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDTDFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=1037311 ACB352_RS03505 WP_011284961.1 666028..667065(+) (sepM) [Streptococcus pyogenes strain Isolate 22]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATACTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment