Detailed information NTG1036799

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ACB336_RS02345
• Genome accession: NZ_CP167000
• Coordinates: 438615..439616 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain Isolate 33
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 433615..444616

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB336_RS02320 (ACB336_02325)	-	434289..434972 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
ACB336_RS02325 (ACB336_02330)	-	435183..436109 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
ACB336_RS02330 (ACB336_02335)	-	436254..436631 (-)	378	WP_002985686.1	VOC family protein	-
ACB336_RS02335 (ACB336_02340)	-	436642..437307 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
ACB336_RS02340 (ACB336_02345)	-	437356..438441 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
ACB336_RS02345 (ACB336_02350)	ccpA	438615..439616 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
ACB336_RS02350 (ACB336_02355)	-	439747..440745 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
ACB336_RS02355 (ACB336_02360)	-	440747..442081 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
ACB336_RS02360 (ACB336_02365)	thrS	442503..444446 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=1036799 ACB336_RS02345 WP_002985680.1 438615..439616(+) (ccpA) [Streptococcus pyogenes strain Isolate 33]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=1036799 ACB336_RS02345 WP_002985680.1 438615..439616(+) (ccpA) [Streptococcus pyogenes strain Isolate 33]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559