Detailed information NTG1036767

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ACB350_RS06500
• Genome accession: NZ_CP166999
• Coordinates: 1255096..1256133 (-)
• Length: 345 a.a.
• NCBI ID: WP_129304106.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 34
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1250096..1261133

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB350_RS06480 (ACB350_06480)	-	1250846..1251472 (+)	627	WP_002989076.1	A24 family peptidase	-
ACB350_RS06485 (ACB350_06485)	rlmN	1251554..1252634 (-)	1081	Protein_1234	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
ACB350_RS06490 (ACB350_06490)	-	1252638..1253258 (-)	621	WP_002992791.1	YutD family protein	-
ACB350_RS06495 (ACB350_06495)	-	1253706..1254682 (-)	977	Protein_1236	LacI family DNA-binding transcriptional regulator	-
ACB350_RS06500 (ACB350_06500)	sepM	1255096..1256133 (-)	1038	WP_129304106.1	SepM family pheromone-processing serine protease	Regulator
ACB350_RS06505 (ACB350_06505)	coaD	1256120..1256611 (-)	492	WP_030127407.1	pantetheine-phosphate adenylyltransferase	-
ACB350_RS06510 (ACB350_06510)	rsmD	1256601..1257140 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACB350_RS06515 (ACB350_06515)	asnA	1257263..1258255 (-)	993	WP_002983817.1	aspartate--ammonia ligase	-
ACB350_RS06520 (ACB350_06520)	arcC	1258568..1259518 (-)	951	WP_010922501.1	carbamate kinase	-
ACB350_RS06525 (ACB350_06525)	-	1259538..1260869 (-)	1332	WP_011054719.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37554.29 Da
• Isoelectric Point: 9.7537

>NTDB_id=1036767 ACB350_RS06500 WP_129304106.1 1255096..1256133(-) (sepM) [Streptococcus pyogenes strain Isolate 34]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAENTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1036767 ACB350_RS06500 WP_129304106.1 1255096..1256133(-) (sepM) [Streptococcus pyogenes strain Isolate 34]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAAATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGGAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGTGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69