Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ACA346_RS08240 Genome accession   NZ_CP166970
Coordinates   1596263..1598506 (+) Length   747 a.a.
NCBI ID   WP_217374156.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NX1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1591263..1603506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA346_RS08215 (ACA346_08215) - 1592198..1593106 (+) 909 WP_217374153.1 neutral zinc metallopeptidase -
  ACA346_RS08220 (ACA346_08220) - 1593187..1594038 (-) 852 WP_130554559.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  ACA346_RS08225 (ACA346_08225) - 1594167..1594901 (-) 735 WP_217374154.1 amino acid ABC transporter ATP-binding protein -
  ACA346_RS08230 (ACA346_08230) - 1594903..1595583 (-) 681 WP_277837686.1 amino acid ABC transporter permease -
  ACA346_RS08235 (ACA346_08235) - 1595703..1595933 (-) 231 WP_130554562.1 DUF1797 family protein -
  ACA346_RS08240 (ACA346_08240) clpE 1596263..1598506 (+) 2244 WP_217374156.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  ACA346_RS08245 (ACA346_08245) - 1598653..1599120 (+) 468 WP_217374157.1 NUDIX hydrolase -
  ACA346_RS08250 (ACA346_08250) - 1599167..1599475 (+) 309 WP_217374158.1 DUF1827 family protein -
  ACA346_RS08255 (ACA346_08255) ileS 1599538..1602327 (-) 2790 WP_418127576.1 isoleucine--tRNA ligase -
  ACA346_RS08260 (ACA346_08260) - 1602338..1602493 (-) 156 WP_418126693.1 hypothetical protein -
  ACA346_RS08265 (ACA346_08265) - 1602445..1602780 (-) 336 WP_318151041.1 hypothetical protein -

Sequence

Protein


Download         Length: 747 a.a.        Molecular weight: 83301.62 Da        Isoelectric Point: 5.0599

>NTDB_id=1036443 ACA346_RS08240 WP_217374156.1 1596263..1598506(+) (clpE) [Streptococcus parasuis strain NX1]
MLCTNCKINDATIHLYANMNGKQQKVDLCHNCYQIMKTDPNNAVLRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
DQTPPTQAGGGNGGDRFNQPNAGRTQTVPQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPHKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREVILFIDEIHEIVGAG
SAGDGNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQNKYQDYHHVKYSP
EAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRIIDAENRKEQATRDEDYEKAAYYRDQIAKYK
EMQKATISEEDIPLITEKEIEAIIEQKTNIPVGELKEKEQSQLIHLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGNVEASVGFGAAMEGRTQSVLDQLGNFFTPEFMN
RFDGIIEFQPLTKENLLQIVSLMLEDVNRRLSTNGIRLQVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLE
NPNEKDLRGVMTNNGTIQIKAQTLKEK

Nucleotide


Download         Length: 2244 bp        

>NTDB_id=1036443 ACA346_RS08240 WP_217374156.1 1596263..1598506(+) (clpE) [Streptococcus parasuis strain NX1]
ATGCTCTGTACAAACTGTAAAATAAATGATGCTACCATTCATCTCTATGCAAATATGAATGGCAAACAACAAAAAGTTGA
CCTTTGCCATAATTGTTATCAAATTATGAAAACAGATCCAAATAATGCTGTTTTACGTGGCTTAGGGGACTTAACTAATC
CAAACAATATGGATCCTTTTAGTGAATTTTTCAATCATTTAGGTGGTTACCCTGGTAATACCCCAGCTGGTAAGAATCGA
GATCAAACACCACCTACTCAAGCAGGCGGTGGCAACGGTGGTGATCGATTCAATCAACCAAATGCTGGTCGAACCCAAAC
AGTCCCGCAACCAAATGGATTGCTGGAAGAATTTGGGATTAATGTTACTGAGATTGCACGACGTGGAGATATTGACCCCG
TTATTGGACGCGATCAAGAAATCACTCGGGTGATTGAAATTTTGAACCGTCGCACCAAAAACAACCCCGTTCTTATCGGT
GAACCCGGTGTTGGTAAAACTGCAGTCGTTGAAGGACTAGCACAAAAAATTGTAGACGGGGACGTTCCACATAAACTTCA
AAACAAAGAAGTCATTCGATTAGACGTTGTCAGCCTTGTTCAAGGAACAGGAATCCGAGGTCAATTTGAAGAACGCATGC
AAAAACTCATGGAAGAAATTCGGAACCGACGTGAAGTTATTCTCTTCATTGATGAAATTCATGAGATTGTCGGAGCTGGT
TCTGCAGGAGATGGGAACATGGATGCGGGCAATATTCTAAAACCCGCCCTCGCTCGTGGTGAAATGCAACTGGTTGGTGC
TACTACTTTAAATGAATACCGCATTATTGAAAAAGATGCAGCTCTTGAACGTCGGATGCAACCTGTAAAAGTTGACGAAC
CAAGCGTTGAAGAAACAATCACTATCTTAAAAGGTATTCAGAATAAATACCAAGACTACCACCATGTAAAATATTCCCCT
GAGGCAATTGAAGCTGCGGCCGTATTATCCAACCGCTATATTCAAGACCGATTCTTACCTGACAAAGCGATTGATTTGCT
AGACGAAGCTGGGTCAAAAATGAACTTAACCTTGAACTTCGTGGATCCTAAAGAAATTGACCAACGGATAATTGATGCCG
AAAATCGTAAAGAACAAGCAACTCGTGATGAAGATTACGAAAAAGCTGCCTATTATCGTGACCAAATTGCTAAATATAAA
GAAATGCAAAAGGCAACGATTAGTGAGGAGGATATTCCTCTCATTACCGAAAAAGAAATTGAAGCCATCATTGAACAAAA
AACAAATATCCCCGTTGGCGAGCTGAAAGAAAAAGAACAGTCTCAATTGATACATTTGGCTAGTGATCTCAAGGCGCATG
TTATTGGACAAGACGATGCTGTTGATAAGATTGCAAAAGCAATCCGTCGCAATCGTGTAGGACTTGGAGCACCAAATCGT
CCAATTGGTTCCTTCTTATTCGTAGGACCTACTGGCGTCGGTAAAACAGAATTATCAAAACAATTAGCCATTGAGCTCTT
CGGTTCAGCGGACAGCATGATTCGATTTGATATGTCTGAATATATGGAAAAACACGCAGTTGCAAAACTAGTCGGTGCCC
CTCCTGGATATGTGGGGTATGAAGAAGCTGGCCAACTAACAGAAAAAGTCCGTCGCAATCCATACTCACTCATTCTCCTT
GATGAAGTTGAAAAGGCGCACCCAGATGTGATGCACATGTTCCTACAAGTTCTTGATGACGGTCGACTGACAGATGGACA
AGGGCGAACAGTCAGCTTCAAAGATACCATTATCATTATGACTTCAAATGCTGGTACAGGTAATGTTGAGGCCAGCGTGG
GATTTGGAGCCGCTATGGAAGGTCGTACACAATCTGTTCTTGACCAACTCGGTAATTTCTTCACTCCCGAATTCATGAAC
CGCTTCGATGGAATTATTGAATTCCAACCACTTACAAAAGAAAATCTGCTCCAAATTGTCAGTCTCATGCTGGAAGACGT
CAACCGTCGCTTATCTACAAACGGTATTCGACTACAAGTGACCGATAAAGTAAAGGAAAAATTAGTTGATCTTGGTTACG
ATCCTAAAATGGGTGCACGTCCCCTTCGCAGGACCATTCAAGACCAAATTGAAGATGCCATTACCGATTTCTATTTAGAG
AATCCTAATGAGAAAGATTTACGAGGTGTCATGACTAATAATGGCACCATCCAAATCAAAGCTCAAACGCTAAAAGAAAA
ATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(651-722)

AAA domain (Cdc48 subfamily) (AAA_2)

(480-643)

ATPase family associated with various cellular activities (AAA) (AAA)

(157-276)

AAA lid domain (AAA_lid_9)

(295-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.708

99.866

0.826
  clpE Streptococcus pneumoniae D39

82.708

99.866

0.826
  clpE Streptococcus pneumoniae R6

82.708

99.866

0.826
  clpE Streptococcus pneumoniae TIGR4

82.708

99.866

0.826
  clpE Streptococcus mutans UA159

82.796

99.598

0.825
  clpC Lactococcus lactis subsp. cremoris KW2

76.066

97.323

0.74
  clpC Bacillus subtilis subsp. subtilis str. 168

50.698

86.345

0.438
  clpC Streptococcus mutans UA159

46.615

87.015

0.406
  clpC Streptococcus pneumoniae TIGR4

47.444

83.802

0.398
  clpC Streptococcus pneumoniae Rx1

47.444

83.802

0.398
  clpC Streptococcus pneumoniae D39

47.444

83.802

0.398
  clpC Streptococcus thermophilus LMD-9

46.965

83.802

0.394
  clpC Streptococcus thermophilus LMG 18311

46.645

83.802

0.391
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.688

82.865

0.387

Multiple sequence alignment