Detailed information NTG1036416

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACA346_RS00950
• Genome accession: NZ_CP166970
• Coordinates: 176050..178503 (+)
• Length: 817 a.a.
• NCBI ID: WP_418126958.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain NX1
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 171050..183503

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACA346_RS00915 (ACA346_00915)	nusG	171161..171700 (+)	540	WP_216806176.1	transcription termination/antitermination protein NusG	-
ACA346_RS00920 (ACA346_00920)	-	171956..172147 (-)	192	WP_217374555.1	helix-turn-helix transcriptional regulator	-
ACA346_RS00930 (ACA346_00930)	rpsB	172950..173726 (+)	777	WP_277837367.1	30S ribosomal protein S2	-
ACA346_RS00935 (ACA346_00935)	tsf	173882..174922 (+)	1041	WP_217374556.1	translation elongation factor Ts	-
ACA346_RS00940 (ACA346_00940)	-	175084..175422 (-)	339	WP_130554180.1	thioredoxin domain-containing protein	-
ACA346_RS00945 (ACA346_00945)	-	175586..176044 (+)	459	WP_418127497.1	CtsR family transcriptional regulator	-
ACA346_RS00950 (ACA346_00950)	clpC	176050..178503 (+)	2454	WP_418126958.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ACA346_RS00955 (ACA346_00955)	-	178632..179669 (+)	1038	WP_418126959.1	AAA family ATPase	-
ACA346_RS00960 (ACA346_00960)	pnuC	179679..180494 (+)	816	WP_418126960.1	nicotinamide riboside transporter PnuC	-
ACA346_RS00965 (ACA346_00965)	-	180487..181269 (+)	783	WP_418126961.1	NUDIX domain-containing protein	-
ACA346_RS00970 (ACA346_00970)	dusB	181303..182307 (-)	1005	WP_172036533.1	tRNA dihydrouridine synthase DusB	-
ACA346_RS00975 (ACA346_00975)	hslO	182300..183166 (-)	867	WP_217374561.1	Hsp33 family molecular chaperone HslO	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90666.16 Da
• Isoelectric Point: 5.7872

>NTDB_id=1036416 ACA346_RS00950 WP_418126958.1 176050..178503(+) (clpC) [Streptococcus parasuis strain NX1]
MKISTGLQRVFEDAQLIAQRYACDHLETWHILLAFVINHDTVAGAVLAEYPMSISDFEHATFVVTEKVYREELDKFNILP
SSKRLDDTAQFARKIAEVVKAKELGSEHLFQAMLLDKRSTASQILDKVGFHFEEIEDEFRFVDLRKNLEYRAGFTKEDLK
AIRSVMKGGKAKTASVGQMMGMPPTAQSGGLEDYTRDLTALAREGKIEPVIGRDAEISRMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAEGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGDATV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQVEETGLSTIDKALMAGKYKTVSKLLIKTTEKNLLSQNDDLEV
TEDDILETLSRLSGIPVAKLSQSDTKKYLNLEKELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGAADLSKDHKEVEKRIFEELKKTYRPEFINRIDEKVVF
HSLTESDMLDVVKVMVKPLIVVAASKGILLKFQPSALKLLAKEGYDPEMGARPLRRLLQTKLEDPMAEMLLREDLGAGMV
LKVGVKGNQLKFESVNE

Nucleotide

• Length: 2454 bp

>NTDB_id=1036416 ACA346_RS00950 WP_418126958.1 176050..178503(+) (clpC) [Streptococcus parasuis strain NX1]
ATGAAAATTTCAACAGGCTTACAACGGGTTTTTGAAGATGCTCAGTTGATTGCCCAACGTTATGCATGCGATCATTTAGA
AACGTGGCATATTTTGCTAGCATTTGTCATCAATCACGATACGGTAGCTGGTGCTGTTTTGGCAGAATACCCAATGAGTA
TTTCAGATTTCGAACATGCTACTTTTGTTGTTACAGAAAAAGTGTACCGTGAAGAATTGGATAAATTTAATATTCTACCC
TCCTCAAAGAGATTAGACGATACAGCTCAGTTCGCTAGAAAGATTGCAGAAGTCGTTAAGGCAAAAGAATTAGGAAGCGA
GCATTTGTTTCAGGCAATGCTGTTAGACAAACGTTCAACCGCAAGTCAAATTCTAGATAAAGTAGGTTTTCATTTTGAAG
AGATAGAAGATGAATTCCGTTTTGTTGATTTACGTAAAAACTTAGAGTATCGTGCAGGGTTTACCAAAGAGGATTTGAAA
GCTATCCGTAGCGTGATGAAAGGTGGAAAGGCTAAAACAGCAAGTGTAGGTCAAATGATGGGCATGCCACCAACTGCTCA
AAGTGGTGGATTGGAGGATTATACACGAGATTTGACAGCCTTAGCTCGCGAGGGGAAAATTGAACCTGTTATTGGTCGCG
ATGCTGAAATTTCACGGATGATTCAAATTCTATCACGTAAAACGAAGAACAATCCTGTTTTGGTTGGCGATGCAGGTGTT
GGGAAAACAGCACTAGCATTAGGTCTTGCTCAGCGTGTTGCAGAAGGAGATGTTCCTGTCAGTTTAGCAAAGATGCGTGT
TTTGGAACTTGATTTGATGAATGTTATTGCAGGAACTCGTTTCCGTGGTGACTTTGAAGAGCGGATGAATAATATCATCA
ATGATATTGAAGAAGATGGTCAGGTTATCCTCTTTATCGATGAATTACATACTATTATGGGGTCGGGTTCGGGAATTGAT
TCAACCTTAGATGCTGCCAATATTCTCAAACCGGCCTTGGCTCGAGGGACCCTACGCACTGTTGGTGCAACGACACAGGA
TGAATACCAAAAGCATATTGAAAAAGATGCTGCCCTGGTCCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTTG
AGGACAGTATTGCCATTTTGACCGGGCTTAAAGGGACTTTTGAAAAATACCATAGGGTCCGTATTGGAGATGCGACTGTT
GAGACAGCTGTGACTTACGCCAAGAGGTATCTGACTAGTAAAAACTTGCCAGACTCAGCAATTGACTTGTTAGATGAAGC
CAGTGCAACGGTACAAAATAGAGTGAAAGGGCAGGTTGAAGAAACAGGTCTTTCAACTATTGATAAAGCTTTGATGGCTG
GAAAATACAAGACTGTCAGTAAGCTCTTAATCAAGACTACAGAAAAGAATCTGTTGAGTCAAAACGATGACTTAGAAGTG
ACAGAAGATGACATTTTGGAAACACTTAGTCGCTTATCAGGTATCCCAGTAGCCAAGCTCAGCCAATCAGATACTAAGAA
GTACCTGAATCTGGAAAAAGAATTGCACAAACGTGTGATTGGGCAGGAAGAAGCTATTTCTGCCGTTAGTAGAGCTATCC
GCCGTAATCAGTCGGGGATTCGGACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTAGGACCAACTGGTGTCGGTAAG
ACTGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGCTATGTTGGCTATGAAGAAGGTGGCGAATTAACAGAAA
AAGTTCGTAATAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGACGGTGTCTTGACCGATAGTAAAGGTCGCAAGGTTGATTTCTCCAATACAGTCATTATCATGACATC
AAACTTGGGGGCAACAGCTCTTCGCGATGACAAGACCGTTGGGTTTGGTGCGGCTGATCTGTCCAAAGACCACAAGGAAG
TGGAGAAACGCATTTTTGAAGAATTGAAAAAGACCTATCGTCCTGAATTTATCAACCGTATCGATGAAAAGGTAGTCTTC
CACAGCTTGACAGAATCCGATATGTTGGATGTTGTCAAAGTGATGGTGAAGCCATTGATTGTGGTTGCTGCGAGCAAGGG
AATCCTCCTGAAATTCCAACCATCAGCCCTCAAATTGTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCTCGCCCTC
TTCGTCGGTTGCTCCAAACAAAATTGGAAGACCCGATGGCAGAAATGCTTTTGCGTGAAGATCTTGGAGCAGGTATGGTT
CTGAAAGTGGGTGTCAAAGGTAACCAACTCAAATTTGAGAGTGTGAATGAATAG

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (372-449)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-798)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-137)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-49)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	70.885	99.633	0.706
clpC	Streptococcus pneumoniae D39	70.885	99.633	0.706
clpC	Streptococcus pneumoniae TIGR4	70.762	99.633	0.705
clpC	Streptococcus mutans UA159	65.725	99.633	0.655
clpC	Streptococcus thermophilus LMG 18311	65.074	99.878	0.65
clpC	Streptococcus thermophilus LMD-9	65.074	99.878	0.65
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.499	100	0.494
clpC	Bacillus subtilis subsp. subtilis str. 168	43.22	100	0.437