Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ACA109_RS12960 Genome accession   NZ_CP166872
Coordinates   2618894..2619559 (+) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain 24EBSta0529     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2613894..2624559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA109_RS12935 (ACA109_12935) - 2615302..2616063 (+) 762 WP_371256894.1 alpha/beta hydrolase -
  ACA109_RS12940 (ACA109_12940) - 2616308..2616763 (+) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  ACA109_RS12945 (ACA109_12945) - 2616885..2616986 (+) 102 WP_000731972.1 SE2200 family small protein -
  ACA109_RS12950 (ACA109_12950) - 2617046..2618470 (-) 1425 WP_371256895.1 alkaline phosphatase -
  ACA109_RS12955 (ACA109_12955) - 2618668..2618868 (+) 201 WP_000604727.1 hypothetical protein -
  ACA109_RS12960 (ACA109_12960) braR 2618894..2619559 (+) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  ACA109_RS12965 (ACA109_12965) braS 2619570..2620457 (+) 888 WP_000143422.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  ACA109_RS12970 (ACA109_12970) - 2620565..2621320 (+) 756 WP_000923768.1 ABC transporter ATP-binding protein -
  ACA109_RS12975 (ACA109_12975) - 2621317..2623317 (+) 2001 WP_371256896.1 FtsX-like permease family protein -
  ACA109_RS12980 (ACA109_12980) - 2623985..2624098 (+) 114 WP_072468803.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=1035858 ACA109_RS12960 WP_000697883.1 2618894..2619559(+) (braR) [Staphylococcus aureus strain 24EBSta0529]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1035858 ACA109_RS12960 WP_000697883.1 2618894..2619559(+) (braR) [Staphylococcus aureus strain 24EBSta0529]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATTCTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment