Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACA109_RS02420 Genome accession   NZ_CP166872
Coordinates   476331..477047 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 24EBSta0529     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 471331..482047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA109_RS02400 (ACA109_02400) - 472425..473375 (+) 951 WP_000790320.1 LacI family DNA-binding transcriptional regulator -
  ACA109_RS02405 (ACA109_02405) - 473524..475008 (+) 1485 WP_371257085.1 sucrose-6-phosphate hydrolase -
  ACA109_RS02410 (ACA109_02410) - 475005..475964 (+) 960 WP_371257086.1 carbohydrate kinase -
  ACA109_RS02415 (ACA109_02415) - 476152..476259 (-) 108 WP_041204320.1 hypothetical protein -
  ACA109_RS02420 (ACA109_02420) agrA 476331..477047 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACA109_RS02425 (ACA109_02425) agrC 477066..478358 (-) 1293 WP_001807128.1 quorum-sensing sensor histidine kinase AgrC -
  ACA109_RS02430 (ACA109_02430) agrD 478383..478523 (-) 141 WP_001094303.1 cyclic lactone autoinducer peptide AgrD -
  ACA109_RS02435 (ACA109_02435) - 478525..479088 (-) 564 WP_001105715.1 accessory gene regulator AgrB -
  ACA109_RS02440 (ACA109_02440) hld 479378..479458 (+) 81 WP_000046023.1 delta-hemolysin -
  ACA109_RS02445 (ACA109_02445) - 480056..480841 (-) 786 WP_162646874.1 carbon-nitrogen family hydrolase -
  ACA109_RS02450 (ACA109_02450) - 481202..481828 (-) 627 WP_162646873.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1035820 ACA109_RS02420 WP_000688492.1 476331..477047(-) (agrA) [Staphylococcus aureus strain 24EBSta0529]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1035820 ACA109_RS02420 WP_000688492.1 476331..477047(-) (agrA) [Staphylococcus aureus strain 24EBSta0529]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment