Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AB6A22_RS05730 Genome accession   NZ_CP166297
Coordinates   1164863..1165519 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain FCW119-1M2     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1159863..1170519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6A22_RS05700 (AB6A22_05705) oppF 1160392..1161309 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  AB6A22_RS05705 (AB6A22_05710) - 1161416..1162603 (+) 1188 WP_164691548.1 putative glycoside hydrolase -
  AB6A22_RS05710 (AB6A22_05715) - 1162721..1163299 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  AB6A22_RS05715 (AB6A22_05720) spx 1163478..1163873 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  AB6A22_RS05720 (AB6A22_05725) - 1163931..1164587 (-) 657 WP_003155033.1 TerC family protein -
  AB6A22_RS05725 (AB6A22_05730) - 1164770..1164880 (+) 111 Protein_1065 adaptor protein MecA -
  AB6A22_RS05730 (AB6A22_05735) mecA 1164863..1165519 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  AB6A22_RS05735 (AB6A22_05740) - 1165670..1166830 (+) 1161 WP_044053100.1 competence protein CoiA family protein -
  AB6A22_RS05740 (AB6A22_05745) pepF 1167058..1168887 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  AB6A22_RS05745 (AB6A22_05750) - 1168925..1169092 (-) 168 WP_003155026.1 hypothetical protein -
  AB6A22_RS05750 (AB6A22_05755) spxH 1169378..1170280 (-) 903 WP_024085126.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1034043 AB6A22_RS05730 WP_003155032.1 1164863..1165519(+) (mecA) [Bacillus velezensis strain FCW119-1M2]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1034043 AB6A22_RS05730 WP_003155032.1 1164863..1165519(+) (mecA) [Bacillus velezensis strain FCW119-1M2]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment