Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SD311_RS09370 Genome accession   NZ_CP166245
Coordinates   1954488..1955204 (+) Length   238 a.a.
NCBI ID   WP_017723432.1    Uniprot ID   A0A418IKK6
Organism   Staphylococcus sp. KG4-3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1949488..1960204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SD311_RS09345 (SD311_009350) - 1949876..1950505 (+) 630 WP_107552438.1 nitroreductase family protein -
  SD311_RS09350 (SD311_009355) - 1950869..1951654 (+) 786 WP_017723437.1 carbon-nitrogen family hydrolase -
  SD311_RS09355 (SD311_009360) - 1952421..1952990 (+) 570 WP_107552630.1 accessory gene regulator AgrB -
  SD311_RS09360 (SD311_009365) agrD 1952993..1953154 (+) 162 WP_107552632.1 cyclic lactone autoinducer peptide AgrD -
  SD311_RS09365 (SD311_009370) agrC 1953180..1954475 (+) 1296 WP_119604204.1 quorum-sensing sensor histidine kinase AgrC -
  SD311_RS09370 (SD311_009375) agrA 1954488..1955204 (+) 717 WP_017723432.1 quorum-sensing response regulator AgrA Regulator
  SD311_RS09375 (SD311_009380) - 1955240..1956205 (-) 966 WP_119604205.1 carbohydrate kinase -
  SD311_RS09380 (SD311_009385) - 1956202..1957686 (-) 1485 WP_017723430.1 sucrose-6-phosphate hydrolase -
  SD311_RS09385 (SD311_009390) - 1957771..1958733 (-) 963 WP_107551653.1 LacI family DNA-binding transcriptional regulator -
  SD311_RS09390 (SD311_009395) - 1958929..1959114 (+) 186 WP_135092815.1 hypothetical protein -
  SD311_RS09395 (SD311_009400) - 1959503..1959727 (-) 225 WP_017723427.1 sulfurtransferase TusA family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27925.74 Da        Isoelectric Point: 5.4062

>NTDB_id=1033966 SD311_RS09370 WP_017723432.1 1954488..1955204(+) (agrA) [Staphylococcus sp. KG4-3]
MKIFICEDDERQREHMVSIINNYIMIEEKPMEIEVATADPYDILERSKNINDIGCYFLDIQLDADINGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPDELKSRVIDCLETSESRLKLLSKESSVETIELKRGSNSIYVQYDDVM
FFESSSKSHRLIAHLDNRQIEFYGNLKEIDQLDKRFFRCHNSFVVNRHNIESIDSKSRVVYFKNNEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1033966 SD311_RS09370 WP_017723432.1 1954488..1955204(+) (agrA) [Staphylococcus sp. KG4-3]
ATGAAAATATTCATTTGCGAAGATGATGAAAGACAACGTGAACATATGGTCTCAATTATAAATAACTATATTATGATTGA
AGAAAAACCAATGGAAATTGAAGTCGCAACAGCTGATCCTTATGACATTTTAGAACGCTCAAAGAACATTAATGATATAG
GATGTTACTTTTTAGATATTCAACTAGATGCTGACATCAATGGTATCAAGCTTGCAAGTGAAATACGCAAACATGATCCG
GTTGGTAATATTATTTTTGTTACAAGTCATAGTGAACTGACATACTTAACATTTGTCTACAAGGTTGCAGCAATGGATTT
CATTTTCAAAGATGATCCAGACGAATTAAAATCAAGAGTGATTGATTGCTTAGAAACATCTGAATCACGATTAAAACTAC
TTTCAAAAGAAAGTAGTGTTGAAACAATAGAATTAAAACGTGGTAGCAATTCTATTTATGTACAATATGACGATGTAATG
TTCTTCGAATCATCTAGTAAATCCCATCGTTTAATTGCACATCTCGATAATCGTCAAATCGAATTCTATGGAAACCTAAA
AGAAATTGATCAGTTAGATAAACGTTTCTTTAGATGTCATAATAGTTTCGTAGTAAATAGACACAATATCGAGTCCATCG
ACTCTAAATCACGCGTAGTTTATTTTAAAAACAATGAACATTGTTATGCATCTGTAAGAAATGTTAAAAAGATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A418IKK6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

84.874

100

0.849

Multiple sequence alignment