Detailed information NTG1031685

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QTG71_RS10435
• Genome accession: NZ_CP165776
• Coordinates: 2078033..2079076 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN05
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2073033..2084076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QTG71_RS10405 (QTG71_010405)	-	2073451..2074707 (-)	1257	WP_001795438.1	aminopeptidase	-
QTG71_RS10410 (QTG71_010410)	-	2074710..2074910 (-)	201	WP_000180461.1	DUF1128 family protein	-
QTG71_RS10415 (QTG71_010415)	-	2075057..2075521 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QTG71_RS10420 (QTG71_010420)	-	2075528..2075803 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QTG71_RS10425 (QTG71_010425)	-	2076081..2077298 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QTG71_RS10430 (QTG71_010430)	vraR	2077414..2078043 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
QTG71_RS10435 (QTG71_010435)	vraS	2078033..2079076 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QTG71_RS10440 (QTG71_010440)	liaF	2079073..2079774 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QTG71_RS10445 (QTG71_010445)	-	2079789..2080175 (-)	387	WP_001110179.1	hypothetical protein	-
QTG71_RS10450 (QTG71_010450)	map	2080392..2081150 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QTG71_RS10455 (QTG71_010455)	-	2081669..2082655 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
QTG71_RS10460 (QTG71_010460)	-	2083145..2083558 (-)	414	WP_001549145.1	hypothetical protein	-
QTG71_RS10465 (QTG71_010465)	-	2083587..2083697 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1031685 QTG71_RS10435 WP_001017131.1 2078033..2079076(-) (vraS) [Staphylococcus aureus strain BSN05]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1031685 QTG71_RS10435 WP_001017131.1 2078033..2079076(-) (vraS) [Staphylococcus aureus strain BSN05]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1