Detailed information NTG1031648

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QTG74_RS13875
• Genome accession: NZ_CP165774
• Coordinates: 2750275..2751162 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN03
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2745275..2756162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QTG74_RS13845 (QTG74_013840)	-	2745294..2745386 (+)	93	WP_010956583.1	hypothetical protein	-
QTG74_RS13850 (QTG74_013845)	-	2745494..2745991 (-)	498	WP_001065268.1	glutathione peroxidase	-
QTG74_RS13855 (QTG74_013850)	-	2746001..2746261 (-)	261	WP_001789910.1	hypothetical protein	-
QTG74_RS13860 (QTG74_013855)	-	2746643..2746756 (-)	114	WP_001791776.1	hypothetical protein	-
QTG74_RS13865 (QTG74_013860)	-	2747415..2749415 (-)	2001	WP_000776751.1	ABC transporter permease	-
QTG74_RS13870 (QTG74_013865)	-	2749412..2750167 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QTG74_RS13875 (QTG74_013870)	braS	2750275..2751162 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QTG74_RS13880 (QTG74_013875)	braR	2751173..2751838 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QTG74_RS13885 (QTG74_013880)	-	2751864..2752064 (-)	201	WP_000604728.1	hypothetical protein	-
QTG74_RS13890 (QTG74_013885)	-	2752262..2753686 (+)	1425	WP_000953744.1	alkaline phosphatase	-
QTG74_RS13895 (QTG74_013890)	-	2753746..2753847 (-)	102	WP_000731972.1	SE2200 family small protein	-
QTG74_RS13900 (QTG74_013895)	-	2753969..2754424 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QTG74_RS13905 (QTG74_013900)	-	2754669..2755430 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1031648 QTG74_RS13875 WP_000143419.1 2750275..2751162(-) (braS) [Staphylococcus aureus strain BSN03]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1031648 QTG74_RS13875 WP_000143419.1 2750275..2751162(-) (braS) [Staphylococcus aureus strain BSN03]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997