Detailed information NTG1031643

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QTG74_RS09945
• Genome accession: NZ_CP165774
• Coordinates: 2007896..2008939 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN03
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2002896..2013939

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QTG74_RS09915 (QTG74_009915)	-	2003314..2004570 (-)	1257	WP_001795438.1	aminopeptidase	-
QTG74_RS09920 (QTG74_009920)	-	2004573..2004773 (-)	201	WP_000180461.1	DUF1128 family protein	-
QTG74_RS09925 (QTG74_009925)	-	2004920..2005384 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QTG74_RS09930 (QTG74_009930)	-	2005391..2005666 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QTG74_RS09935 (QTG74_009935)	-	2005944..2007161 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QTG74_RS09940 (QTG74_009940)	vraR	2007277..2007906 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
QTG74_RS09945 (QTG74_009945)	vraS	2007896..2008939 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QTG74_RS09950 (QTG74_009950)	liaF	2008936..2009637 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QTG74_RS09955 (QTG74_009955)	-	2009652..2010038 (-)	387	WP_001110179.1	hypothetical protein	-
QTG74_RS09960 (QTG74_009960)	map	2010255..2011013 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QTG74_RS09965 (QTG74_009965)	-	2011541..2012527 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
QTG74_RS09970 (QTG74_009970)	-	2013017..2013430 (-)	414	WP_001549145.1	hypothetical protein	-
QTG74_RS09975 (QTG74_009975)	-	2013459..2013569 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1031643 QTG74_RS09945 WP_001017131.1 2007896..2008939(-) (vraS) [Staphylococcus aureus strain BSN03]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1031643 QTG74_RS09945 WP_001017131.1 2007896..2008939(-) (vraS) [Staphylococcus aureus strain BSN03]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1