Detailed information NTG1031315

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HQU64_RS14350
• Genome accession: NZ_CP165650
• Coordinates: 2818087..2818974 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain B0354
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2813087..2823974

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HQU64_RS14320 (HQU64_14315)	-	2813106..2813198 (+)	93	WP_010956583.1	hypothetical protein	-
HQU64_RS14325 (HQU64_14320)	-	2813306..2813803 (-)	498	WP_001065268.1	glutathione peroxidase	-
HQU64_RS14330 (HQU64_14325)	-	2813813..2814073 (-)	261	WP_001789910.1	hypothetical protein	-
HQU64_RS14335 (HQU64_14330)	-	2814455..2814568 (-)	114	WP_001791776.1	hypothetical protein	-
HQU64_RS14340 (HQU64_14335)	-	2815227..2817227 (-)	2001	WP_000776751.1	ABC transporter permease	-
HQU64_RS14345 (HQU64_14340)	-	2817224..2817979 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HQU64_RS14350 (HQU64_14345)	braS	2818087..2818974 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HQU64_RS14355 (HQU64_14350)	braR	2818985..2819650 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HQU64_RS14360 (HQU64_14355)	-	2819676..2819876 (-)	201	WP_000604728.1	hypothetical protein	-
HQU64_RS14365 (HQU64_14360)	-	2820074..2821498 (+)	1425	WP_000953744.1	alkaline phosphatase	-
HQU64_RS14370 (HQU64_14365)	-	2821558..2821659 (-)	102	WP_000731972.1	SE2200 family small protein	-
HQU64_RS14375 (HQU64_14370)	-	2821781..2822236 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HQU64_RS14380 (HQU64_14375)	-	2822481..2823242 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1031315 HQU64_RS14350 WP_000143419.1 2818087..2818974(-) (braS) [Staphylococcus aureus strain B0354]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1031315 HQU64_RS14350 WP_000143419.1 2818087..2818974(-) (braS) [Staphylococcus aureus strain B0354]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997