Detailed information NTG1031310

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HQU64_RS10420
• Genome accession: NZ_CP165650
• Coordinates: 2075774..2076817 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain B0354
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2070774..2081817

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HQU64_RS10390 (HQU64_10390)	-	2071192..2072448 (-)	1257	WP_001795438.1	aminopeptidase	-
HQU64_RS10395 (HQU64_10395)	-	2072451..2072651 (-)	201	WP_000180461.1	DUF1128 family protein	-
HQU64_RS10400 (HQU64_10400)	-	2072798..2073262 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
HQU64_RS10405 (HQU64_10405)	-	2073269..2073544 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
HQU64_RS10410 (HQU64_10410)	-	2073822..2075039 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
HQU64_RS10415 (HQU64_10415)	vraR	2075155..2075784 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
HQU64_RS10420 (HQU64_10420)	vraS	2075774..2076817 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
HQU64_RS10425 (HQU64_10425)	liaF	2076814..2077515 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
HQU64_RS10430 (HQU64_10430)	-	2077530..2077916 (-)	387	WP_001110179.1	hypothetical protein	-
HQU64_RS10435 (HQU64_10435)	map	2078133..2078891 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
HQU64_RS10440 (HQU64_10440)	-	2079419..2080405 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
HQU64_RS10445 (HQU64_10445)	-	2080895..2081308 (-)	414	WP_001549145.1	hypothetical protein	-
HQU64_RS10450 (HQU64_10450)	-	2081337..2081447 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1031310 HQU64_RS10420 WP_001017131.1 2075774..2076817(-) (vraS) [Staphylococcus aureus strain B0354]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1031310 HQU64_RS10420 WP_001017131.1 2075774..2076817(-) (vraS) [Staphylococcus aureus strain B0354]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1