Detailed information NTG1031241

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QTG70_RS09790
• Genome accession: NZ_CP165642
• Coordinates: 1998839..1999882 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN04
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1993839..2004882

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QTG70_RS09760 (QTG70_09785)	-	1994260..1995516 (-)	1257	WP_001795108.1	aminopeptidase	-
QTG70_RS09765 (QTG70_09790)	-	1995519..1995719 (-)	201	WP_000180460.1	DUF1128 family protein	-
QTG70_RS09770 (QTG70_09795)	-	1995866..1996330 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QTG70_RS09775 (QTG70_09800)	-	1996337..1996612 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QTG70_RS09780 (QTG70_09805)	-	1996890..1998107 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QTG70_RS09785 (QTG70_09810)	vraR	1998220..1998849 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QTG70_RS09790 (QTG70_09815)	vraS	1998839..1999882 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QTG70_RS09795 (QTG70_09820)	liaF	1999879..2000580 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QTG70_RS09800 (QTG70_09825)	-	2000595..2000981 (-)	387	WP_001110179.1	hypothetical protein	-
QTG70_RS09805 (QTG70_09830)	map	2001198..2001956 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QTG70_RS09810 (QTG70_09835)	-	2002487..2003473 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
QTG70_RS09815 (QTG70_09840)	-	2003904..2004317 (-)	414	WP_001557448.1	hypothetical protein	-
QTG70_RS09820 (QTG70_09845)	-	2004346..2004456 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1031241 QTG70_RS09790 WP_001017131.1 1998839..1999882(-) (vraS) [Staphylococcus aureus strain BSN04]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1031241 QTG70_RS09790 WP_001017131.1 1998839..1999882(-) (vraS) [Staphylococcus aureus strain BSN04]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1