Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | QTG70_RS00365 | Genome accession | NZ_CP165642 |
| Coordinates | 80275..81624 (-) | Length | 449 a.a. |
| NCBI ID | WP_000815646.1 | Uniprot ID | Q9XB96 |
| Organism | Staphylococcus aureus strain BSN04 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 47456..81624 | 80275..81624 | within | 0 |
Gene organization within MGE regions
Location: 47456..81624
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QTG70_RS00205 (QTG70_00205) | - | 47465..49390 (+) | 1926 | WP_000790094.1 | heavy metal translocating P-type ATPase | - |
| QTG70_RS00210 (QTG70_00210) | - | 50718..51974 (+) | 1257 | WP_000566670.1 | MrcB family domain-containing protein | - |
| QTG70_RS00215 (QTG70_00215) | - | 52389..52628 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| QTG70_RS00220 (QTG70_00220) | - | 52660..53334 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| QTG70_RS00225 (QTG70_00225) | - | 53425..54408 (-) | 984 | Protein_42 | protein rep | - |
| QTG70_RS00230 (QTG70_00230) | mobV | 54653..55915 (-) | 1263 | WP_000119405.1 | MobV family relaxase | - |
| QTG70_RS00235 (QTG70_00235) | bleO | 56422..56826 (-) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| QTG70_RS00240 (QTG70_00240) | aadD1 | 57043..57813 (-) | 771 | WP_001795128.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| QTG70_RS00245 (QTG70_00245) | - | 58006..58680 (-) | 675 | WP_374936581.1 | IS6-like element IS257 family transposase | - |
| QTG70_RS00250 (QTG70_00250) | - | 58945..59688 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| QTG70_RS00255 (QTG70_00255) | - | 59785..60213 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| QTG70_RS00260 (QTG70_00260) | mecA | 60259..62268 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| QTG70_RS00265 (QTG70_00265) | mecR1 | 62365..64122 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| QTG70_RS00270 (QTG70_00270) | mecI | 64122..64493 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| QTG70_RS00275 (QTG70_00275) | psm-mec | 64578..64646 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| QTG70_RS00280 (QTG70_00280) | - | 64980..66110 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| QTG70_RS00285 (QTG70_00285) | cstB | 66224..67558 (-) | 1335 | Protein_54 | persulfide dioxygenase-sulfurtransferase CstB | - |
| QTG70_RS00290 (QTG70_00290) | - | 67591..68655 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| QTG70_RS00295 (QTG70_00295) | cstR | 68791..69051 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| QTG70_RS00300 (QTG70_00300) | - | 69051..69689 (+) | 639 | Protein_57 | sulfite exporter TauE/SafE family protein | - |
| QTG70_RS00305 (QTG70_00305) | - | 70034..70696 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| QTG70_RS00310 (QTG70_00310) | - | 71088..71147 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| QTG70_RS00315 (QTG70_00315) | erm(A) | 71230..71961 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| QTG70_RS00320 (QTG70_00320) | - | 72087..72869 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| QTG70_RS00325 (QTG70_00325) | - | 73020..73397 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| QTG70_RS00330 (QTG70_00330) | - | 73404..75296 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| QTG70_RS00335 (QTG70_00335) | - | 75293..76378 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| QTG70_RS00340 (QTG70_00340) | - | 76497..76814 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| QTG70_RS00345 (QTG70_00345) | - | 76835..77341 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| QTG70_RS00350 (QTG70_00350) | - | 77359..77670 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| QTG70_RS00355 (QTG70_00355) | - | 77757..78107 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| QTG70_RS00360 (QTG70_00360) | ccrB | 78625..80253 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| QTG70_RS00365 (QTG70_00365) | ccrA | 80275..81624 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52607.20 Da Isoelectric Point: 9.9585
>NTDB_id=1031209 QTG70_RS00365 WP_000815646.1 80275..81624(-) (ccrA) [Staphylococcus aureus strain BSN04]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=1031209 QTG70_RS00365 WP_000815646.1 80275..81624(-) (ccrA) [Staphylococcus aureus strain BSN04]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus N315 |
100 |
100 |
1 |
| ccrA | Staphylococcus aureus COL |
74.833 |
100 |
0.748 |