Detailed information NTG1031155

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QTG72_RS09800
• Genome accession: NZ_CP165638
• Coordinates: 1964916..1965959 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN01
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1959916..1970959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QTG72_RS09770 (QTG72_09765)	-	1960337..1961584 (-)	1248	WP_000656302.1	aminopeptidase	-
QTG72_RS09775 (QTG72_09770)	-	1961596..1961796 (-)	201	WP_000180459.1	DUF1128 family protein	-
QTG72_RS09780 (QTG72_09775)	-	1961943..1962407 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
QTG72_RS09785 (QTG72_09780)	-	1962414..1962689 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QTG72_RS09790 (QTG72_09785)	-	1962967..1964184 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
QTG72_RS09795 (QTG72_09790)	vraR	1964297..1964926 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QTG72_RS09800 (QTG72_09795)	vraS	1964916..1965959 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QTG72_RS09805 (QTG72_09800)	liaF	1965956..1966657 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QTG72_RS09810 (QTG72_09805)	-	1966672..1967058 (-)	387	WP_049296041.1	hypothetical protein	-
QTG72_RS09815 (QTG72_09810)	map	1967275..1968033 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
QTG72_RS09820 (QTG72_09815)	-	1968564..1969550 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
QTG72_RS09825 (QTG72_09820)	-	1969728..1970141 (-)	414	WP_001622129.1	hypothetical protein	-
QTG72_RS09830 (QTG72_09825)	-	1970170..1970279 (-)	110	Protein_1901	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1031155 QTG72_RS09800 WP_001017131.1 1964916..1965959(-) (vraS) [Staphylococcus aureus strain BSN01]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1031155 QTG72_RS09800 WP_001017131.1 1964916..1965959(-) (vraS) [Staphylococcus aureus strain BSN01]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1