Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QUR24_RS10135 Genome accession   NZ_CP165634
Coordinates   2032547..2033263 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain BSN13     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2027547..2038263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUR24_RS10105 (QUR24_10100) - 2027766..2028392 (+) 627 WP_000522384.1 nitroreductase family protein -
  QUR24_RS10110 (QUR24_10105) - 2028753..2029538 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  QUR24_RS10115 hld 2030134..2030214 (-) 81 WP_000046022.1 delta-hemolysin -
  QUR24_RS10120 (QUR24_10115) agrB 2030504..2031073 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  QUR24_RS10125 (QUR24_10120) agrD 2031070..2031210 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  QUR24_RS10130 (QUR24_10125) agrC 2031235..2032528 (+) 1294 Protein_1960 quorum-sensing sensor histidine kinase AgrC -
  QUR24_RS10135 (QUR24_10130) agrA 2032547..2033263 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  QUR24_RS10140 (QUR24_10135) - 2033335..2033444 (+) 110 Protein_1962 hypothetical protein -
  QUR24_RS10145 (QUR24_10140) - 2033632..2034591 (-) 960 WP_001253302.1 carbohydrate kinase -
  QUR24_RS10150 (QUR24_10145) - 2034588..2036072 (-) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  QUR24_RS10155 (QUR24_10150) - 2036221..2037171 (-) 951 WP_000790318.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=1031072 QUR24_RS10135 WP_000688498.1 2032547..2033263(+) (agrA) [Staphylococcus aureus strain BSN13]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1031072 QUR24_RS10135 WP_000688498.1 2032547..2033263(+) (agrA) [Staphylococcus aureus strain BSN13]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment