Detailed information NTG1031035

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SL318_RS14585
• Genome accession: NZ_CP165630
• Coordinates: 2865698..2866585 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN54
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2860698..2871585

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SL318_RS14555 (SL318_14570)	-	2860717..2860809 (+)	93	WP_010956583.1	hypothetical protein	-
SL318_RS14560 (SL318_14575)	-	2860917..2861414 (-)	498	WP_001065268.1	glutathione peroxidase	-
SL318_RS14565 (SL318_14580)	-	2861424..2861684 (-)	261	WP_001791974.1	hypothetical protein	-
SL318_RS14570 (SL318_14585)	-	2862066..2862179 (-)	114	Protein_2834	hypothetical protein	-
SL318_RS14575 (SL318_14590)	-	2862838..2864838 (-)	2001	WP_000776751.1	ABC transporter permease	-
SL318_RS14580 (SL318_14595)	-	2864835..2865590 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SL318_RS14585 (SL318_14600)	braS	2865698..2866585 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SL318_RS14590 (SL318_14605)	braR	2866596..2867261 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SL318_RS14595 (SL318_14610)	-	2867287..2867487 (-)	201	WP_000604730.1	hypothetical protein	-
SL318_RS14600 (SL318_14615)	-	2867685..2869109 (+)	1425	WP_000953755.1	alkaline phosphatase	-
SL318_RS14605 (SL318_14620)	-	2869169..2869270 (-)	102	WP_000731976.1	SE2200 family small protein	-
SL318_RS14610 (SL318_14625)	-	2869392..2869847 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SL318_RS14615 (SL318_14630)	-	2870092..2870853 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1031035 SL318_RS14585 WP_000143425.1 2865698..2866585(-) (braS) [Staphylococcus aureus strain BSN54]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1031035 SL318_RS14585 WP_000143425.1 2865698..2866585(-) (braS) [Staphylococcus aureus strain BSN54]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1