Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | SL318_RS00460 | Genome accession | NZ_CP165630 |
| Coordinates | 100565..102193 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain BSN54 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 39658..103564 | 100565..102193 | within | 0 |
Gene organization within MGE regions
Location: 39658..103564
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SL318_RS00180 (SL318_00180) | ccrB | 39658..41286 (-) | 1629 | WP_001631035.1 | cassette chromosome recombinase CcrB | Machinery gene |
| SL318_RS00185 (SL318_00185) | ccrA | 41283..42644 (-) | 1362 | WP_001631036.1 | cassette chromosome recombinase CcrA | Machinery gene |
| SL318_RS00190 (SL318_00190) | - | 42831..43460 (-) | 630 | Protein_35 | hypothetical protein | - |
| SL318_RS00195 (SL318_00195) | - | 43469..43807 (+) | 339 | Protein_36 | recombinase family protein | - |
| SL318_RS00200 (SL318_00200) | - | 43919..44278 (-) | 360 | WP_196506795.1 | hypothetical protein | - |
| SL318_RS00205 (SL318_00205) | - | 44485..44811 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| SL318_RS00210 (SL318_00210) | - | 45141..47066 (+) | 1926 | WP_320234022.1 | heavy metal translocating P-type ATPase | - |
| SL318_RS00215 (SL318_00215) | - | 48161..48790 (+) | 630 | WP_001053439.1 | hypothetical protein | - |
| SL318_RS00220 (SL318_00220) | - | 48805..49047 (+) | 243 | WP_000931963.1 | hypothetical protein | - |
| SL318_RS00225 (SL318_00225) | - | 49446..50297 (+) | 852 | WP_000832687.1 | IS3 family transposase | - |
| SL318_RS00230 (SL318_00230) | arcC | 50397..51326 (-) | 930 | WP_000036756.1 | carbamate kinase | - |
| SL318_RS00235 (SL318_00235) | argF | 51346..52344 (-) | 999 | WP_000793596.1 | ornithine carbamoyltransferase | - |
| SL318_RS00240 (SL318_00240) | - | 52382..53071 (-) | 690 | WP_000272781.1 | Crp/Fnr family transcriptional regulator | - |
| SL318_RS00245 (SL318_00245) | arcD | 53113..54534 (-) | 1422 | WP_000344142.1 | arginine-ornithine antiporter | - |
| SL318_RS00250 (SL318_00250) | arcA | 54620..55855 (-) | 1236 | WP_000249804.1 | arginine deiminase | - |
| SL318_RS00255 (SL318_00255) | - | 56124..56570 (-) | 447 | WP_000711815.1 | arginine repressor | - |
| SL318_RS00260 (SL318_00260) | - | 57143..57825 (+) | 683 | Protein_49 | type I restriction enzyme endonuclease domain-containing protein | - |
| SL318_RS00265 (SL318_00265) | - | 58096..58527 (-) | 432 | WP_000475804.1 | universal stress protein | - |
| SL318_RS00270 (SL318_00270) | - | 59415..59738 (-) | 324 | WP_320234028.1 | replication initiation protein | - |
| SL318_RS00275 (SL318_00275) | - | 59754..60428 (+) | 675 | WP_374936580.1 | IS6 family transposase | - |
| SL318_RS00280 (SL318_00280) | - | 61188..61421 (-) | 234 | WP_000400093.1 | hypothetical protein | - |
| SL318_RS00285 (SL318_00285) | pls | 61667..66091 (+) | 4425 | WP_320234031.1 | plasmin-sensitive LPXTG-anchored glycoprotein Pls | - |
| SL318_RS00290 (SL318_00290) | - | 66215..67831 (+) | 1617 | WP_000393941.1 | hypothetical protein | - |
| SL318_RS00295 (SL318_00295) | - | 67991..69502 (-) | 1512 | WP_000640645.1 | glycosyltransferase | - |
| SL318_RS00300 (SL318_00300) | - | 69525..71183 (-) | 1659 | WP_001621813.1 | Mur ligase family protein | - |
| SL318_RS00305 (SL318_00305) | - | 71177..71575 (-) | 399 | WP_001621810.1 | hypothetical protein | - |
| SL318_RS00310 (SL318_00310) | - | 72657..73913 (+) | 1257 | WP_000566670.1 | MrcB family domain-containing protein | - |
| SL318_RS00315 (SL318_00315) | - | 74328..74567 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| SL318_RS00320 (SL318_00320) | - | 74599..75273 (-) | 675 | WP_374936581.1 | IS6-like element IS257 family transposase | - |
| SL318_RS00325 (SL318_00325) | - | 75364..76347 (-) | 984 | Protein_62 | protein rep | - |
| SL318_RS00330 (SL318_00330) | mobV | 76592..77854 (-) | 1263 | WP_000119405.1 | MobV family relaxase | - |
| SL318_RS00335 (SL318_00335) | bleO | 78362..78766 (-) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| SL318_RS00340 (SL318_00340) | aadD1 | 78983..79753 (-) | 771 | WP_001795128.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| SL318_RS00345 (SL318_00345) | - | 79946..80620 (-) | 675 | WP_374936581.1 | IS6-like element IS257 family transposase | - |
| SL318_RS00350 (SL318_00350) | - | 80885..81628 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| SL318_RS00355 (SL318_00355) | - | 81725..82153 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| SL318_RS00360 (SL318_00360) | mecA | 82199..84208 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| SL318_RS00365 (SL318_00365) | mecR1 | 84305..86062 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| SL318_RS00370 (SL318_00370) | mecI | 86062..86433 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| SL318_RS00375 (SL318_00375) | psm-mec | 86518..86586 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| SL318_RS00380 (SL318_00380) | - | 86920..88050 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| SL318_RS00385 (SL318_00385) | cstB | 88164..89498 (-) | 1335 | Protein_74 | persulfide dioxygenase-sulfurtransferase CstB | - |
| SL318_RS00390 (SL318_00390) | - | 89531..90595 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| SL318_RS00395 (SL318_00395) | cstR | 90731..90991 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| SL318_RS00400 (SL318_00400) | - | 90991..91629 (+) | 639 | Protein_77 | sulfite exporter TauE/SafE family protein | - |
| SL318_RS00405 (SL318_00405) | - | 91974..92636 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| SL318_RS00410 (SL318_00410) | - | 93028..93087 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| SL318_RS00415 (SL318_00415) | erm(A) | 93170..93901 (+) | 732 | WP_320234976.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| SL318_RS00420 (SL318_00420) | - | 94027..94809 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| SL318_RS00425 (SL318_00425) | - | 94960..95337 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| SL318_RS00430 (SL318_00430) | - | 95344..97236 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| SL318_RS00435 (SL318_00435) | - | 97233..98318 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| SL318_RS00440 (SL318_00440) | - | 98437..98754 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| SL318_RS00445 (SL318_00445) | - | 98775..99281 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| SL318_RS00450 (SL318_00450) | - | 99299..99610 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| SL318_RS00455 (SL318_00455) | - | 99697..100047 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SL318_RS00460 (SL318_00460) | ccrB | 100565..102193 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| SL318_RS00465 (SL318_00465) | ccrA | 102215..103564 (-) | 1350 | WP_196581173.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=1030995 SL318_RS00460 WP_001186602.1 100565..102193(-) (ccrB) [Staphylococcus aureus strain BSN54]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=1030995 SL318_RS00460 WP_001186602.1 100565..102193(-) (ccrB) [Staphylococcus aureus strain BSN54]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |