Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AB3D65_RS10590 Genome accession   NZ_CP165606
Coordinates   2141603..2142259 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain BP1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2136603..2147259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3D65_RS10570 (AB3D65_10570) spxH 2136842..2137744 (+) 903 WP_369546810.1 protease adaptor protein SpxH -
  AB3D65_RS10575 (AB3D65_10575) - 2138030..2138197 (+) 168 WP_003155026.1 hypothetical protein -
  AB3D65_RS10580 (AB3D65_10580) pepF 2138235..2140064 (-) 1830 WP_369546811.1 oligoendopeptidase F Regulator
  AB3D65_RS10585 (AB3D65_10585) - 2140292..2141452 (-) 1161 WP_369546812.1 competence protein CoiA family protein -
  AB3D65_RS10590 (AB3D65_10590) mecA 2141603..2142259 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  AB3D65_RS10595 (AB3D65_10595) - 2142535..2143191 (+) 657 WP_151296678.1 TerC family protein -
  AB3D65_RS10600 (AB3D65_10600) spx 2143249..2143644 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  AB3D65_RS10605 (AB3D65_10605) - 2143824..2144402 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  AB3D65_RS10610 (AB3D65_10610) - 2144520..2145707 (-) 1188 WP_084191224.1 putative glycoside hydrolase -
  AB3D65_RS10615 (AB3D65_10615) oppF 2145814..2146731 (-) 918 WP_369546815.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1030805 AB3D65_RS10590 WP_003155032.1 2141603..2142259(-) (mecA) [Bacillus velezensis strain BP1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1030805 AB3D65_RS10590 WP_003155032.1 2141603..2142259(-) (mecA) [Bacillus velezensis strain BP1]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATTGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment