Detailed information NTG1030606

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: AB6W33_RS02970
• Genome accession: NZ_CP163561
• Coordinates: 510805..511878 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain GBS-B4009
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 505805..516878

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB6W33_RS02940 (AB6W33_02945)	-	506698..507762 (+)	1065	WP_000021302.1	MmcQ/YjbR family DNA-binding protein	-
AB6W33_RS02945 (AB6W33_02950)	asnA	507876..508868 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
AB6W33_RS02950 (AB6W33_02955)	-	508913..509362 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
AB6W33_RS02955 (AB6W33_02960)	rsmD	509492..510031 (+)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
AB6W33_RS02960 (AB6W33_02965)	-	510043..510333 (+)	291	WP_000384889.1	hypothetical protein	-
AB6W33_RS02965 (AB6W33_02970)	coaD	510330..510815 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
AB6W33_RS02970 (AB6W33_02975)	sepM	510805..511878 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
AB6W33_RS02975 (AB6W33_02980)	-	511953..513285 (+)	1333	Protein_502	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
AB6W33_RS02980 (AB6W33_02985)	-	513354..513932 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
AB6W33_RS02985 (AB6W33_02990)	rlmN	513983..515089 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
AB6W33_RS02990 (AB6W33_02995)	-	515089..515604 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=1030606 AB6W33_RS02970 WP_000796095.1 510805..511878(+) (sepM) [Streptococcus agalactiae strain GBS-B4009]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=1030606 AB6W33_RS02970 WP_000796095.1 510805..511878(+) (sepM) [Streptococcus agalactiae strain GBS-B4009]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658