Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   AB6M99_RS10160 Genome accession   NZ_CP163513
Coordinates   2065874..2066815 (-) Length   313 a.a.
NCBI ID   WP_121835586.1    Uniprot ID   A0A3L9DTR7
Organism   Streptococcus hillyeri strain S23-3001-2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2060874..2071815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M99_RS10135 (AB6M99_10135) - 2061487..2061873 (+) 387 WP_121835578.1 DUF2809 domain-containing protein -
  AB6M99_RS10145 (AB6M99_10145) - 2062334..2063290 (+) 957 WP_121835580.1 S66 peptidase family protein -
  AB6M99_RS10150 (AB6M99_10150) - 2063348..2064538 (-) 1191 WP_121835582.1 acetate kinase -
  AB6M99_RS10155 (AB6M99_10155) - 2064619..2065812 (-) 1194 WP_121835584.1 acetate kinase -
  AB6M99_RS10160 (AB6M99_10160) comYH 2065874..2066815 (-) 942 WP_121835586.1 class I SAM-dependent methyltransferase Machinery gene
  AB6M99_RS10165 (AB6M99_10165) comYG 2066895..2067290 (-) 396 WP_121835588.1 competence type IV pilus minor pilin ComGG Machinery gene
  AB6M99_RS10170 (AB6M99_10170) comYF 2067268..2067723 (-) 456 WP_121835590.1 competence type IV pilus minor pilin ComGF Machinery gene
  AB6M99_RS10175 (AB6M99_10175) comGE 2067689..2067983 (-) 295 Protein_1949 competence type IV pilus minor pilin ComGE -
  AB6M99_RS10180 (AB6M99_10180) comYD 2067955..2068362 (-) 408 WP_121835591.1 competence type IV pilus minor pilin ComGD Machinery gene
  AB6M99_RS10185 (AB6M99_10185) - 2068659..2070074 (-) 1416 WP_121835595.1 peptidoglycan amidohydrolase family protein -
  AB6M99_RS10190 (AB6M99_10190) - 2070203..2070430 (-) 228 WP_121835597.1 phage holin -
  AB6M99_RS10195 (AB6M99_10195) - 2070427..2070732 (-) 306 WP_121835599.1 hypothetical protein -
  AB6M99_RS10200 (AB6M99_10200) - 2070736..2070876 (-) 141 WP_183121663.1 hypothetical protein -
  AB6M99_RS10205 (AB6M99_10205) - 2070908..2071363 (-) 456 WP_121835603.1 DUF1366 domain-containing protein -
  AB6M99_RS10210 (AB6M99_10210) - 2071360..2071545 (-) 186 WP_121835605.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35450.35 Da        Isoelectric Point: 4.3766

>NTDB_id=1030321 AB6M99_RS10160 WP_121835586.1 2065874..2066815(-) (comYH) [Streptococcus hillyeri strain S23-3001-2]
MNFEKIETAYELILENIQLIENDLRTNIYDALIEQNSFYLGAEGATETVAQNNETLKALDLTQEEWRRAFQFIFIKAGQT
EVLQANHQFTPDSIGFILLFLMETLTDKEQLDVIEIGSGTGNLAHTLVTNSRKHLDYMGIELDDLLIDLSASIADVMGSS
VSFVQEDAVRPQILKESDVIISDLPVGYYPNDEIARRYTVAATDEHTYAHHLLMEQSLKYLKADGLALFLAPTDLLTSPQ
SPLLKKWLSGYASVLAVITLPETLFGRKDKSKAIFILQKQSSQPRETFVYPITDLQNQDVIVEFMTKFKKWSE

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1030321 AB6M99_RS10160 WP_121835586.1 2065874..2066815(-) (comYH) [Streptococcus hillyeri strain S23-3001-2]
ATGAATTTTGAAAAGATTGAAACAGCCTATGAGCTGATTTTAGAAAACATCCAACTGATTGAGAATGACCTTAGAACCAA
TATCTATGACGCTTTGATTGAGCAAAATAGTTTTTATCTTGGTGCTGAAGGGGCAACTGAGACGGTTGCTCAAAATAATG
AGACGTTAAAAGCACTTGACCTCACACAGGAAGAATGGCGCCGTGCCTTCCAATTTATCTTTATCAAGGCTGGGCAAACT
GAAGTGTTGCAGGCAAATCATCAATTTACACCAGACAGCATCGGTTTTATCCTACTCTTTTTAATGGAGACCCTGACAGA
TAAGGAACAACTTGATGTCATTGAGATTGGTTCGGGAACGGGTAACCTTGCCCATACGTTAGTGACTAATAGCCGTAAAC
ACCTAGATTATATGGGGATTGAACTGGATGATTTACTGATTGACCTTTCTGCCTCAATTGCAGATGTCATGGGGTCTAGC
GTCAGCTTTGTCCAAGAAGATGCCGTTCGCCCTCAAATTCTAAAAGAGAGTGATGTCATCATCAGTGACCTCCCTGTTGG
CTATTATCCCAATGATGAGATTGCGCGCCGCTATACAGTAGCTGCCACGGATGAGCACACCTACGCCCACCACCTGCTGA
TGGAACAGTCGCTTAAGTATCTAAAAGCCGACGGCTTAGCATTGTTTTTAGCTCCAACTGACCTTCTAACCAGTCCTCAG
TCTCCTCTTTTGAAAAAATGGCTGAGCGGCTATGCTAGTGTCCTTGCTGTTATCACATTACCTGAGACCCTCTTTGGACG
AAAAGATAAGTCTAAAGCTATCTTTATTTTGCAAAAGCAGAGCAGTCAACCGAGAGAAACTTTCGTCTATCCTATAACAG
ATTTACAAAATCAAGATGTTATAGTAGAGTTTATGACCAAATTCAAAAAATGGTCGGAGTGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(73-290)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L9DTR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

69.649

100

0.696
  comYH Streptococcus mutans UA140

69.649

100

0.696

Multiple sequence alignment