Detailed information NTG1030315

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: AB6M99_RS10070
• Genome accession: NZ_CP163513
• Coordinates: 2045512..2046564 (-)
• Length: 350 a.a.
• NCBI ID: WP_121836456.1
• Uniprot ID: A0A3L9DJW6
• Organism: Streptococcus hillyeri strain S23-3001-2
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 2040512..2051564

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB6M99_RS10050 (AB6M99_10050)	-	2040545..2041096 (-)	552	WP_183121699.1	nucleotidyltransferase family protein	-
AB6M99_RS10055 (AB6M99_10055)	tkt	2041144..2043117 (-)	1974	WP_121836458.1	transketolase	-
AB6M99_RS10060 (AB6M99_10060)	-	2043254..2044414 (+)	1161	WP_121836465.1	ISAs1 family transposase	-
AB6M99_RS10065 (AB6M99_10065)	amiF	2044579..2045502 (-)	924	WP_121836457.1	ATP-binding cassette domain-containing protein	Regulator
AB6M99_RS10070 (AB6M99_10070)	amiE	2045512..2046564 (-)	1053	WP_121836456.1	ABC transporter ATP-binding protein	Regulator
AB6M99_RS10075 (AB6M99_10075)	amiD	2046574..2047500 (-)	927	WP_121836455.1	oligopeptide ABC transporter permease OppC	Regulator
AB6M99_RS10080 (AB6M99_10080)	amiC	2047500..2049002 (-)	1503	WP_121836454.1	ABC transporter permease	Regulator
AB6M99_RS10085 (AB6M99_10085)	amiA	2049067..2051037 (-)	1971	WP_369350711.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 350 a.a.
• Molecular weight: 38956.67 Da
• Isoelectric Point: 5.2883

>NTDB_id=1030315 AB6M99_RS10070 WP_121836456.1 2045512..2046564(-) (amiE) [Streptococcus hillyeri strain S23-3001-2]
MTETKNVILSAEDVVVEFDVRDRVLTAIRSVSLELVEGEVLALVGESGSGKSVLTKTFTGMLESNGRVASGKITYRGQDL
TSINSHSDWEKIRGSKIATIFQDPMTSLNPIKTIGAQISEVIIKHQGVSKEEARELSIDYMNKVGIPNAEKRFNDYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQKEYNFTTIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEDIFYDPRHPYTWSLLSSLPQLATESGELFSIPGTPPSLYAPIKGDAFALRSEYAMQIDFEEPAPKFKVSDHHWAK
TWLLHPEAPKVEKPEVIQNLHEKISRKMLK

Nucleotide

• Length: 1053 bp

>NTDB_id=1030315 AB6M99_RS10070 WP_121836456.1 2045512..2046564(-) (amiE) [Streptococcus hillyeri strain S23-3001-2]
ATGACAGAAACTAAAAATGTAATTTTATCAGCCGAAGATGTGGTCGTGGAATTTGATGTCCGTGACCGTGTTTTGACAGC
AATCCGTAGTGTATCTTTAGAGCTTGTAGAAGGTGAAGTTCTCGCTCTTGTTGGTGAATCAGGTTCGGGGAAATCTGTTT
TAACGAAAACTTTTACAGGTATGCTAGAGTCAAATGGTCGTGTTGCTTCTGGAAAAATCACTTATCGTGGTCAAGATTTA
ACAAGTATTAATTCACATTCGGACTGGGAAAAAATTCGTGGTTCAAAAATTGCGACGATTTTCCAAGATCCAATGACCAG
TCTTAATCCGATTAAAACAATCGGTGCTCAAATTTCAGAAGTCATCATCAAGCATCAAGGAGTTTCGAAAGAAGAAGCTC
GCGAACTCTCCATAGACTACATGAATAAAGTTGGTATCCCAAATGCGGAAAAACGTTTCAATGATTATCCGTTCCAGTAT
TCAGGAGGGATGCGTCAACGTATCGTTATCGCAATTGCTCTTGCCTGTCGTCCAGATGTGCTTATCTGTGATGAACCGAC
AACGGCTCTTGATGTGACGATTCAGGCTCAAATTATTGATCTTTTGAAGTCTCTTCAAAAAGAATATAATTTCACAACTA
TCTTTATCACGCATGACCTCGGTGTCGTTGCCTCTATCGCTGACAAGGTTGCGGTAATGTATGCTGGTGAAATTGTTGAG
TTTGGTACAGTTGAAGATATTTTTTATGACCCACGTCATCCTTATACATGGAGCCTTTTATCTTCGCTACCTCAGTTGGC
AACAGAGTCTGGTGAGTTATTCTCTATCCCGGGAACTCCTCCGTCACTCTACGCGCCTATAAAAGGAGATGCATTTGCTC
TTCGTTCTGAATATGCAATGCAGATTGACTTTGAAGAACCGGCACCTAAATTTAAAGTTTCGGATCACCACTGGGCTAAA
ACTTGGTTGCTCCATCCAGAGGCTCCCAAAGTTGAAAAACCAGAAGTTATCCAAAATCTTCATGAGAAAATTTCTCGTAA
AATGTTGAAATAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A3L9DJW6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	83.621	99.429	0.831
amiE	Streptococcus thermophilus LMG 18311	82.471	99.429	0.82
amiE	Streptococcus thermophilus LMD-9	82.471	99.429	0.82
oppD	Streptococcus mutans UA159	56.765	97.143	0.551