Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AB6M99_RS04925 Genome accession   NZ_CP163513
Coordinates   1040878..1041723 (+) Length   281 a.a.
NCBI ID   WP_121834481.1    Uniprot ID   A0A3L9DZS8
Organism   Streptococcus hillyeri strain S23-3001-2     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1035878..1046723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M99_RS04900 (AB6M99_04900) - 1036288..1036728 (+) 441 WP_121834477.1 GNAT family N-acetyltransferase -
  AB6M99_RS04905 (AB6M99_04905) - 1036814..1038352 (+) 1539 WP_121834478.1 ABC-F family ATP-binding cassette domain-containing protein -
  AB6M99_RS04910 (AB6M99_04910) - 1038395..1038790 (+) 396 WP_121834479.1 SMI1/KNR4 family protein -
  AB6M99_RS04915 (AB6M99_04915) murA 1039124..1040392 (+) 1269 WP_369351153.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AB6M99_RS04920 (AB6M99_04920) - 1040488..1040676 (+) 189 WP_121834480.1 DNA-directed RNA polymerase subunit beta -
  AB6M99_RS04925 (AB6M99_04925) endA 1040878..1041723 (+) 846 WP_121834481.1 DNA/RNA non-specific endonuclease Machinery gene
  AB6M99_RS04930 (AB6M99_04930) - 1041787..1042722 (-) 936 WP_369351154.1 dihydroorotate oxidase -
  AB6M99_RS04935 (AB6M99_04935) - 1043048..1043743 (+) 696 WP_121834483.1 phosphoglycerate mutase -
  AB6M99_RS04940 (AB6M99_04940) - 1043938..1044702 (+) 765 WP_121834484.1 formate/nitrite transporter family protein -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30352.73 Da        Isoelectric Point: 6.8534

>NTDB_id=1030293 AB6M99_RS04925 WP_121834481.1 1040878..1041723(+) (endA) [Streptococcus hillyeri strain S23-3001-2]
MNKKQNKTGLSLLALLVTVAVGLFGGSSTGLFDRLGISLTGHQTQQAASHIEAAEGTPSQALAESVLSSEVRKQLGTIEW
NGAGAFIINDNKTSLNADVASLPYATNQTKRVQGKVVPVNGNALLAKSTRQYKNREQTGQGRTDFRPAGWHQIHDLKGEF
DHAIDRGHLIGYALVGGLSGFDASTSNPENIAVQTAWSNQANLENSTGQNYYESLVRKALDNNKRVRYRVTLIYEGDNLI
ASGSHLEAKSSDGELEFNVFVPNVQDGLTVDYYSGKITTVE

Nucleotide


Download         Length: 846 bp        

>NTDB_id=1030293 AB6M99_RS04925 WP_121834481.1 1040878..1041723(+) (endA) [Streptococcus hillyeri strain S23-3001-2]
ATGAATAAAAAACAAAACAAAACGGGTTTATCACTTTTAGCTTTGCTTGTAACGGTTGCTGTTGGACTTTTTGGTGGAAG
TTCTACGGGACTGTTTGATCGATTAGGCATTTCGTTAACAGGTCATCAGACGCAACAAGCAGCTAGTCACATTGAAGCAG
CAGAAGGGACACCTTCTCAAGCTTTAGCTGAGTCAGTTTTATCTAGCGAAGTTAGAAAACAGCTAGGCACTATCGAATGG
AACGGTGCGGGAGCTTTCATCATAAATGACAATAAAACGTCACTCAATGCTGATGTAGCAAGTCTTCCCTATGCTACCAA
TCAGACAAAACGTGTACAAGGGAAAGTAGTACCAGTAAATGGTAATGCTCTCTTAGCAAAAAGTACGCGTCAATATAAAA
ATCGAGAGCAGACAGGGCAGGGAAGAACGGACTTTCGTCCTGCTGGCTGGCATCAAATTCATGATTTGAAAGGTGAATTT
GATCATGCTATTGATAGAGGTCACTTGATTGGATATGCACTTGTTGGTGGTTTGTCAGGCTTTGATGCGTCAACAAGTAA
TCCTGAAAACATCGCTGTCCAAACAGCGTGGTCAAATCAAGCGAATTTAGAAAATTCAACAGGTCAAAATTATTACGAAT
CACTCGTTCGTAAAGCCTTAGATAATAATAAACGCGTTCGTTATCGTGTGACCTTAATCTATGAAGGAGATAACCTCATT
GCTTCAGGTAGTCATCTAGAGGCAAAGTCCTCAGATGGTGAGTTAGAGTTTAATGTCTTTGTTCCAAATGTTCAAGATGG
TTTAACGGTTGATTACTATAGTGGGAAAATTACCACAGTTGAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(85-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L9DZS8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

64.681

83.63

0.541
  endA Streptococcus pneumoniae D39

64.681

83.63

0.541
  endA Streptococcus pneumoniae R6

64.681

83.63

0.541
  endA Streptococcus pneumoniae TIGR4

64.681

83.63

0.541

Multiple sequence alignment