Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   LLA12_RS08645 Genome accession   NZ_LT599049
Coordinates   1805952..1808282 (-) Length   776 a.a.
NCBI ID   WP_021722107.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain A12     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1800952..1813282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLA12_RS08615 (LLA12_01842) - 1801542..1802525 (-) 984 WP_021722104.1 LacI family DNA-binding transcriptional regulator -
  LLA12_RS08620 (LLA12_01843) purB 1802659..1803954 (-) 1296 WP_021722105.1 adenylosuccinate lyase -
  LLA12_RS08625 (LLA12_01844) aroD 1804151..1804831 (-) 681 WP_003129440.1 type I 3-dehydroquinate dehydratase -
  LLA12_RS08635 (LLA12_01846) - 1805094..1805297 (-) 204 WP_021722106.1 DUF2969 family protein -
  LLA12_RS08640 (LLA12_01847) trxA 1805541..1805855 (-) 315 WP_003129442.1 thioredoxin -
  LLA12_RS08645 (LLA12_01848) mutS/mutS2 1805952..1808282 (-) 2331 WP_021722107.1 endonuclease MutS2 Machinery gene
  LLA12_RS08650 (LLA12_01849) - 1808327..1808887 (-) 561 WP_003129445.1 CvpA family protein -
  LLA12_RS08655 (LLA12_01850) - 1809046..1810011 (-) 966 WP_003129446.1 NAD(P)/FAD-dependent oxidoreductase -
  LLA12_RS08660 (LLA12_01851) ccpA 1810150..1811148 (-) 999 WP_021722108.1 catabolite control protein A Regulator
  LLA12_RS08665 (LLA12_01852) - 1811363..1812451 (+) 1089 WP_021722109.1 M24 family metallopeptidase -

Sequence

Protein


Download         Length: 776 a.a.        Molecular weight: 87318.23 Da        Isoelectric Point: 6.8396

>NTDB_id=1028894 LLA12_RS08645 WP_021722107.1 1805952..1808282(-) (mutS/mutS2) [Lactococcus lactis subsp. lactis strain A12]
MNKKILQILEYDKVKEQFMNALTTAQGQQELKDLKPLTDQEKIQLLFDEVADFRLLTQENGLLNLGKTNDLTEILRRLEL
EASLSGKEFVEIKKVIQLGINIQRFFDEAENVETPSLAITLEKLVDLSPLVKKLEIFDNAGSLYDNASLELMHIRASIKS
HQSEIRKIMQEMLTKNLSSLSENVITIRNDRQVLPVKAENKNKIAGVVHDMSASGQTLYIEPNAVVSLNNKLNQKRIEER
QEITRIYRELASQLKPYSFDIRQNAWLIGHIDFVRAKYLYLAANKATLPELTTDKDITLFAARHPLIEAKIVVANDIKFD
AGLNTIVITGPNTGGKTITLKTVGLLTILAQSGLPILAADGSRIHLFDDIFADIGDEQSIEQSLSTFSSHMTNIVHILAQ
ADENSLVLFDELGAGTDPKEGAALAIAILENLRERNVKTMASTHYPELKAYGVETQRVINASMEFNIDKMQPTYHLQLGV
PGRSNALEISRRLGLPEPIISVASQQISDSEHDVNQMIEKLEEKTREVIESSRNIKKIERENQSLHKDLTKVYNQINRER
EFELEKAQKEAQEVVKKASLEAQEILKNLNDKATLKPHEIIAARKELEGLAPTIDFSKNKVLKKAKAQRGLKQGAEVNVT
SYGQRGKLIRLEKDGRWTVQMGSITTRLNEDEFEVIESPEQIQAKTKNVSKKVTSKVKAQLDLRGMRYEEAELELDNYID
QALLANLIQITIVHGIGTGVIREMVQKKLQKHRHIKSYEYAPINAGGSGATIAILK

Nucleotide


Download         Length: 2331 bp        

>NTDB_id=1028894 LLA12_RS08645 WP_021722107.1 1805952..1808282(-) (mutS/mutS2) [Lactococcus lactis subsp. lactis strain A12]
ATGAATAAAAAAATTCTCCAAATATTGGAATATGATAAAGTCAAAGAACAGTTCATGAATGCTTTGACGACAGCGCAGGG
TCAACAAGAATTAAAAGATTTAAAACCTTTGACAGATCAGGAAAAAATTCAGCTCCTTTTTGATGAAGTTGCTGATTTTC
GCTTATTGACCCAAGAAAATGGCCTATTAAATTTAGGAAAAACAAATGATTTAACAGAAATACTCAGACGTCTAGAGCTT
GAAGCCAGTCTTTCAGGCAAGGAATTCGTTGAAATAAAAAAAGTGATTCAATTAGGGATTAATATTCAACGCTTTTTTGA
TGAAGCTGAAAATGTTGAAACACCTTCACTAGCTATTACTTTGGAAAAATTGGTTGATTTATCACCATTAGTCAAAAAAT
TAGAAATTTTTGATAATGCGGGAAGTCTTTATGATAATGCCAGTCTCGAATTGATGCATATCCGTGCTTCAATCAAGAGT
CATCAATCAGAAATTCGGAAAATCATGCAGGAAATGCTGACCAAAAATCTCTCATCTTTGAGTGAAAATGTCATCACTAT
CCGAAATGACCGACAAGTGCTTCCTGTAAAAGCAGAAAACAAAAATAAAATTGCTGGTGTAGTTCATGATATGTCTGCTT
CAGGTCAAACGCTTTATATTGAACCAAATGCGGTTGTTTCATTAAATAATAAACTTAATCAAAAGAGAATTGAAGAACGC
CAAGAAATCACAAGAATTTATCGTGAACTCGCTAGTCAATTAAAACCTTATAGCTTTGATATAAGACAAAATGCTTGGCT
GATTGGTCATATTGATTTTGTTCGTGCCAAGTATCTTTATTTAGCAGCGAATAAAGCGACACTTCCAGAATTAACAACCG
ATAAAGATATTACCCTTTTTGCAGCTCGCCATCCTTTGATTGAAGCAAAAATAGTTGTGGCAAATGATATTAAATTTGAT
GCGGGGCTCAATACGATTGTTATTACGGGTCCTAATACGGGTGGGAAGACCATTACTTTGAAAACAGTTGGTTTGTTGAC
AATATTGGCTCAATCAGGTCTGCCAATTTTAGCCGCTGATGGCAGTCGAATTCATCTTTTTGATGATATTTTTGCCGATA
TCGGTGATGAGCAATCCATTGAGCAAAGTTTATCAACTTTCTCAAGTCATATGACTAATATTGTTCATATTTTAGCTCAA
GCAGATGAAAATAGTTTGGTCTTGTTTGATGAACTTGGGGCAGGAACTGATCCAAAAGAAGGAGCGGCTCTTGCTATTGC
TATACTGGAAAATTTACGTGAACGAAATGTGAAAACCATGGCAAGTACTCATTATCCTGAGTTAAAAGCTTATGGGGTCG
AAACGCAACGAGTAATCAATGCAAGTATGGAATTTAACATTGATAAAATGCAACCCACTTATCATTTGCAACTGGGAGTG
CCTGGACGTTCAAATGCCCTGGAAATTTCGAGAAGATTAGGTTTGCCAGAACCCATTATTTCAGTAGCCAGTCAACAAAT
TTCTGACAGTGAGCATGATGTCAATCAGATGATTGAAAAGTTGGAAGAAAAAACGCGTGAAGTGATTGAAAGTTCAAGAA
ATATTAAAAAAATTGAACGAGAAAATCAAAGTTTACATAAAGATTTGACGAAAGTCTATAATCAAATTAATCGCGAGCGC
GAGTTTGAATTAGAAAAAGCACAAAAAGAAGCTCAAGAAGTAGTTAAAAAAGCGAGTCTTGAAGCGCAAGAAATTTTGAA
GAATCTCAATGATAAAGCAACGTTGAAACCACATGAAATTATTGCTGCTAGAAAAGAACTTGAAGGTTTGGCTCCAACCA
TTGATTTTTCTAAAAATAAGGTTTTGAAAAAAGCGAAAGCACAAAGAGGACTTAAGCAAGGGGCTGAAGTTAATGTCACT
TCTTATGGTCAGCGTGGTAAATTGATTCGTTTAGAAAAAGATGGACGTTGGACGGTTCAGATGGGTTCAATCACGACTCG
TTTAAATGAAGATGAATTTGAAGTGATTGAAAGTCCAGAACAAATTCAAGCCAAAACTAAAAATGTCAGCAAGAAGGTGA
CTTCTAAAGTCAAAGCTCAACTTGATTTACGCGGGATGCGTTATGAAGAAGCAGAACTGGAATTGGATAATTATATTGAC
CAAGCTCTACTTGCAAATTTGATTCAAATTACGATTGTTCATGGGATTGGAACGGGTGTTATTCGAGAAATGGTACAGAA
AAAACTTCAAAAACACCGTCATATTAAATCTTATGAATATGCACCAATTAATGCTGGTGGCTCTGGAGCAACGATTGCTA
TTTTGAAGTAA

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(634-672)

MutS domain V (MutS_V)

(326-508)

Smr domain (Smr)

(701-776)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

42.748

100

0.433