Detailed information NTG1027103

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: AB3N25_RS00370
• Genome accession: NZ_CP162552
• Coordinates: 78028..79656 (-)
• Length: 542 a.a.
• NCBI ID: WP_001186596.1
• Uniprot ID: -
• Organism: Mammaliicoccus sciuri strain MSS74
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	59859..81023	78028..79656	within	0

Gene organization within MGE regions

Location: 59859..81023

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3N25_RS00275 (AB3N25_00275)	mecA	59859..61868 (-)	2010	WP_404803328.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
AB3N25_RS00280 (AB3N25_00280)	mecR1	61965..63722 (+)	1758	WP_000952923.1	beta-lactam sensor/signal transducer MecR1	-
AB3N25_RS00285 (AB3N25_00285)	mecI	63722..64093 (+)	372	WP_000369214.1	mecA-type methicillin resistance repressor MecI	-
AB3N25_RS00290 (AB3N25_00290)	psm-mec	64178..64246 (-)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
AB3N25_RS00295 (AB3N25_00295)	-	64566..65714 (+)	1149	WP_000427807.1	ROK family transcriptional regulator	-
AB3N25_RS00300 (AB3N25_00300)	cstB	65828..67162 (-)	1335	Protein_57	persulfide dioxygenase-sulfurtransferase CstB	-
AB3N25_RS00305 (AB3N25_00305)	-	67196..68260 (-)	1065	WP_000438836.1	DsrE/DsrF/DrsH-like family protein	-
AB3N25_RS00310 (AB3N25_00310)	cstR	68396..68656 (+)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
AB3N25_RS00315 (AB3N25_00315)	-	68656..69294 (+)	639	Protein_60	sulfite exporter TauE/SafE family protein	-
AB3N25_RS00320 (AB3N25_00320)	-	69568..70185 (-)	618	WP_000562107.1	CadD family cadmium resistance transporter	-
AB3N25_RS00325 (AB3N25_00325)	-	70266..72680 (-)	2415	WP_000378485.1	cadmium-translocating P-type ATPase CadA	-
AB3N25_RS00330 (AB3N25_00330)	-	72673..73038 (-)	366	WP_000159127.1	metalloregulator ArsR/SmtB family transcription factor	-
AB3N25_RS00335 (AB3N25_00335)	-	73276..73653 (-)	378	WP_001041908.1	DUF6262 family protein	-
AB3N25_RS00340 (AB3N25_00340)	-	73660..75552 (-)	1893	WP_248559301.1	site-specific integrase	-
AB3N25_RS00345 (AB3N25_00345)	-	75747..76070 (-)	324	WP_404803329.1	JAB domain-containing protein	-
AB3N25_RS00350 (AB3N25_00350)	-	76063..76269 (-)	207	WP_001077283.1	hypothetical protein	-
AB3N25_RS00355 (AB3N25_00355)	-	76271..76792 (-)	522	WP_000836008.1	DUF1643 domain-containing protein	-
AB3N25_RS00360 (AB3N25_00360)	-	76811..77122 (-)	312	WP_000833212.1	DUF960 family protein	-
AB3N25_RS00365 (AB3N25_00365)	-	77207..77557 (-)	351	WP_000171449.1	SAUGI family uracil-DNA glycosylase inhibitor	-
AB3N25_RS00370 (AB3N25_00370)	ccrB	78028..79656 (-)	1629	WP_001186596.1	cassette chromosome recombinase CcrB	Machinery gene
AB3N25_RS00375 (AB3N25_00375)	ccrA	79677..81023 (-)	1347	WP_404803330.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62274.15 Da
• Isoelectric Point: 9.7334

>NTDB_id=1027103 AB3N25_RS00370 WP_001186596.1 78028..79656(-) (ccrB) [Mammaliicoccus sciuri strain MSS74]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide

• Length: 1629 bp

>NTDB_id=1027103 AB3N25_RS00370 WP_001186596.1 78028..79656(-) (ccrB) [Mammaliicoccus sciuri strain MSS74]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	86.531	100	0.865