Detailed information NTG1026371

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3452_RS02880
• Genome accession: NZ_CP162478
• Coordinates: 614024..614911 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20816
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 609024..619911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3452_RS02850 (AB3452_02850)	-	609756..610517 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
AB3452_RS02855 (AB3452_02855)	-	610762..611217 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3452_RS02860 (AB3452_02860)	-	611339..611440 (+)	102	WP_000731972.1	SE2200 family small protein	-
AB3452_RS02865 (AB3452_02865)	-	611500..612924 (-)	1425	WP_000953744.1	alkaline phosphatase	-
AB3452_RS02870 (AB3452_02870)	-	613122..613322 (+)	201	WP_000604732.1	hypothetical protein	-
AB3452_RS02875 (AB3452_02875)	braR	613348..614013 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3452_RS02880 (AB3452_02880)	braS	614024..614911 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3452_RS02885 (AB3452_02885)	-	615019..615774 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3452_RS02890 (AB3452_02890)	-	615771..617771 (+)	2001	WP_000776751.1	ABC transporter permease	-
AB3452_RS02895 (AB3452_02895)	-	618430..618543 (+)	114	WP_011447078.1	hypothetical protein	-
AB3452_RS02900 (AB3452_02900)	-	618925..619185 (+)	261	WP_001789910.1	hypothetical protein	-
AB3452_RS02905 (AB3452_02905)	-	619195..619692 (+)	498	WP_001065268.1	glutathione peroxidase	-
AB3452_RS02910 (AB3452_02910)	-	619800..619892 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1026371 AB3452_RS02880 WP_000143419.1 614024..614911(+) (braS) [Staphylococcus aureus strain TUM20816]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1026371 AB3452_RS02880 WP_000143419.1 614024..614911(+) (braS) [Staphylococcus aureus strain TUM20816]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997