Detailed information NTG1026314

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3432_RS11020
• Genome accession: NZ_CP162473
• Coordinates: 2188385..2189272 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20818
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2183385..2194272

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3432_RS10990 (AB3432_10990)	-	2183404..2183496 (+)	93	WP_010956583.1	hypothetical protein	-
AB3432_RS10995 (AB3432_10995)	-	2183604..2184101 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3432_RS11000 (AB3432_11000)	-	2184111..2184371 (-)	261	WP_001789910.1	hypothetical protein	-
AB3432_RS11005 (AB3432_11005)	-	2184753..2184866 (-)	114	WP_011447078.1	hypothetical protein	-
AB3432_RS11010 (AB3432_11010)	-	2185525..2187525 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB3432_RS11015 (AB3432_11015)	-	2187522..2188277 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3432_RS11020 (AB3432_11020)	braS	2188385..2189272 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3432_RS11025 (AB3432_11025)	braR	2189283..2189948 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3432_RS11030 (AB3432_11030)	-	2189974..2190174 (-)	201	WP_000604728.1	hypothetical protein	-
AB3432_RS11035 (AB3432_11035)	-	2190372..2191796 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AB3432_RS11040 (AB3432_11040)	-	2191856..2191957 (-)	102	WP_000731972.1	SE2200 family small protein	-
AB3432_RS11045 (AB3432_11045)	-	2192079..2192534 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3432_RS11050 (AB3432_11050)	-	2192779..2193540 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1026314 AB3432_RS11020 WP_000143419.1 2188385..2189272(-) (braS) [Staphylococcus aureus strain TUM20818]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1026314 AB3432_RS11020 WP_000143419.1 2188385..2189272(-) (braS) [Staphylococcus aureus strain TUM20818]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997