Detailed information NTG1026308

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB3432_RS06950
• Genome accession: NZ_CP162473
• Coordinates: 1416553..1417596 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM20818
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1411553..1422596

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3432_RS06920 (AB3432_06920)	-	1411971..1413227 (-)	1257	WP_108932452.1	aminopeptidase	-
AB3432_RS06925 (AB3432_06925)	-	1413230..1413430 (-)	201	WP_000180461.1	DUF1128 family protein	-
AB3432_RS06930 (AB3432_06930)	-	1413577..1414041 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB3432_RS06935 (AB3432_06935)	-	1414048..1414323 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB3432_RS06940 (AB3432_06940)	-	1414601..1415818 (+)	1218	WP_000037069.1	YihY/virulence factor BrkB family protein	-
AB3432_RS06945 (AB3432_06945)	vraR	1415934..1416563 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
AB3432_RS06950 (AB3432_06950)	vraS	1416553..1417596 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB3432_RS06955 (AB3432_06955)	liaF	1417593..1418294 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB3432_RS06960 (AB3432_06960)	-	1418309..1418695 (-)	387	WP_001110179.1	hypothetical protein	-
AB3432_RS06965 (AB3432_06965)	map	1418912..1419670 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB3432_RS06970 (AB3432_06970)	-	1420257..1421243 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
AB3432_RS06975 (AB3432_06975)	-	1421674..1422087 (-)	414	WP_001549145.1	hypothetical protein	-
AB3432_RS06980 (AB3432_06980)	-	1422116..1422226 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1026308 AB3432_RS06950 WP_001017131.1 1416553..1417596(-) (vraS) [Staphylococcus aureus strain TUM20818]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1026308 AB3432_RS06950 WP_001017131.1 1416553..1417596(-) (vraS) [Staphylococcus aureus strain TUM20818]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1