Detailed information NTG1026158

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3431_RS05505
• Genome accession: NZ_CP162467
• Coordinates: 1044638..1045525 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20823
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1039638..1050525

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3431_RS05475 (AB3431_05475)	-	1039657..1039749 (+)	93	WP_010956583.1	hypothetical protein	-
AB3431_RS05480 (AB3431_05480)	-	1039857..1040354 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3431_RS05485 (AB3431_05485)	-	1040364..1040624 (-)	261	WP_001789910.1	hypothetical protein	-
AB3431_RS05490 (AB3431_05490)	-	1041006..1041119 (-)	114	WP_011447078.1	hypothetical protein	-
AB3431_RS05495 (AB3431_05495)	-	1041778..1043778 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB3431_RS05500 (AB3431_05500)	-	1043775..1044530 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3431_RS05505 (AB3431_05505)	braS	1044638..1045525 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3431_RS05510 (AB3431_05510)	braR	1045536..1046201 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3431_RS05515 (AB3431_05515)	-	1046227..1046427 (-)	201	WP_000604728.1	hypothetical protein	-
AB3431_RS05520 (AB3431_05520)	-	1046625..1048049 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AB3431_RS05525 (AB3431_05525)	-	1048109..1048210 (-)	102	WP_000731972.1	SE2200 family small protein	-
AB3431_RS05530 (AB3431_05530)	-	1048332..1048787 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3431_RS05535 (AB3431_05535)	-	1049032..1049793 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1026158 AB3431_RS05505 WP_000143419.1 1044638..1045525(-) (braS) [Staphylococcus aureus strain TUM20823]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1026158 AB3431_RS05505 WP_000143419.1 1044638..1045525(-) (braS) [Staphylococcus aureus strain TUM20823]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997