Detailed information NTG1026113

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3429_RS05180
• Genome accession: NZ_CP162465
• Coordinates: 993509..994396 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM20825
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 988509..999396

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3429_RS05150 (AB3429_05150)	-	988528..988620 (+)	93	WP_010956583.1	hypothetical protein	-
AB3429_RS05155 (AB3429_05155)	-	988728..989225 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3429_RS05160 (AB3429_05160)	-	989235..989495 (-)	261	WP_001791974.1	hypothetical protein	-
AB3429_RS05165 (AB3429_05165)	-	989877..989990 (-)	114	Protein_979	hypothetical protein	-
AB3429_RS05170 (AB3429_05170)	-	990649..992649 (-)	2001	WP_000776740.1	ABC transporter permease	-
AB3429_RS05175 (AB3429_05175)	-	992646..993401 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3429_RS05180 (AB3429_05180)	braS	993509..994396 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3429_RS05185 (AB3429_05185)	braR	994407..995072 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3429_RS05190 (AB3429_05190)	-	995098..995298 (-)	201	WP_000604727.1	hypothetical protein	-
AB3429_RS05195 (AB3429_05195)	-	995496..996920 (+)	1425	WP_000953748.1	alkaline phosphatase	-
AB3429_RS05200 (AB3429_05200)	-	996980..997081 (-)	102	WP_000731972.1	SE2200 family small protein	-
AB3429_RS05205 (AB3429_05205)	-	997203..997658 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3429_RS05210 (AB3429_05210)	-	997903..998664 (-)	762	Protein_988	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=1026113 AB3429_RS05180 WP_000143417.1 993509..994396(-) (braS) [Staphylococcus aureus strain TUM20825]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1026113 AB3429_RS05180 WP_000143417.1 993509..994396(-) (braS) [Staphylococcus aureus strain TUM20825]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99