Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   AB3429_RS02125 Genome accession   NZ_CP162465
Coordinates   388310..389026 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain TUM20825     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 383310..394026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3429_RS02095 (AB3429_02095) - 383526..384152 (+) 627 WP_000522384.1 nitroreductase family protein -
  AB3429_RS02100 (AB3429_02100) - 384513..385298 (+) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  AB3429_RS02105 (AB3429_02105) - 385897..386031 (-) 135 WP_001823225.1 delta-lysin family phenol-soluble modulin -
  AB3429_RS02110 (AB3429_02110) - 386267..386830 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  AB3429_RS02115 (AB3429_02115) agrD 386834..386974 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  AB3429_RS02120 (AB3429_02120) agrC 386999..388291 (+) 1293 WP_172576662.1 quorum-sensing sensor histidine kinase AgrC -
  AB3429_RS02125 (AB3429_02125) agrA 388310..389026 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  AB3429_RS02130 (AB3429_02130) - 389098..389207 (+) 110 Protein_386 hypothetical protein -
  AB3429_RS02135 (AB3429_02135) - 389395..390354 (-) 960 WP_117201054.1 carbohydrate kinase -
  AB3429_RS02140 (AB3429_02140) - 390351..391835 (-) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  AB3429_RS02145 (AB3429_02145) - 391984..392934 (-) 951 WP_338627744.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1026110 AB3429_RS02125 WP_000688492.1 388310..389026(+) (agrA) [Staphylococcus aureus strain TUM20825]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1026110 AB3429_RS02125 WP_000688492.1 388310..389026(+) (agrA) [Staphylococcus aureus strain TUM20825]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment