Detailed information NTG1026108

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB3429_RS01400
• Genome accession: NZ_CP162465
• Coordinates: 266165..267208 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM20825
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 261165..272208

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3429_RS01370 (AB3429_01370)	-	261593..262849 (-)	1257	WP_001793428.1	aminopeptidase	-
AB3429_RS01375 (AB3429_01375)	-	262852..263052 (-)	201	WP_000180460.1	DUF1128 family protein	-
AB3429_RS01380 (AB3429_01380)	-	263199..263663 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB3429_RS01385 (AB3429_01385)	-	263670..263945 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB3429_RS01390 (AB3429_01390)	-	264223..265434 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
AB3429_RS01395 (AB3429_01395)	vraR	265546..266175 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB3429_RS01400 (AB3429_01400)	vraS	266165..267208 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB3429_RS01405 (AB3429_01405)	liaF	267205..267906 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB3429_RS01410 (AB3429_01410)	-	267921..268307 (-)	387	WP_001110179.1	hypothetical protein	-
AB3429_RS01415 (AB3429_01415)	map	268524..269282 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB3429_RS01420 (AB3429_01420)	-	269813..270799 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
AB3429_RS01425 (AB3429_01425)	-	271289..271702 (-)	414	WP_001837236.1	hypothetical protein	-
AB3429_RS01430 (AB3429_01430)	-	271731..271841 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1026108 AB3429_RS01400 WP_001017131.1 266165..267208(-) (vraS) [Staphylococcus aureus strain TUM20825]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1026108 AB3429_RS01400 WP_001017131.1 266165..267208(-) (vraS) [Staphylococcus aureus strain TUM20825]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1