Detailed information NTG1026060

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3422_RS02450
• Genome accession: NZ_CP162463
• Coordinates: 476375..477262 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20888
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 471375..482262

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3422_RS02420 (AB3422_02420)	-	471394..471486 (+)	93	WP_010956583.1	hypothetical protein	-
AB3422_RS02425 (AB3422_02425)	-	471594..472091 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3422_RS02430 (AB3422_02430)	-	472101..472361 (-)	261	WP_001789910.1	hypothetical protein	-
AB3422_RS02435 (AB3422_02435)	-	472743..472856 (-)	114	WP_001791776.1	hypothetical protein	-
AB3422_RS02440 (AB3422_02440)	-	473515..475515 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB3422_RS02445 (AB3422_02445)	-	475512..476267 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3422_RS02450 (AB3422_02450)	braS	476375..477262 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3422_RS02455 (AB3422_02455)	braR	477273..477938 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3422_RS02460 (AB3422_02460)	-	477964..478164 (-)	201	WP_000604728.1	hypothetical protein	-
AB3422_RS02465 (AB3422_02465)	-	478362..479786 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AB3422_RS02470 (AB3422_02470)	-	479846..479947 (-)	102	WP_000731972.1	SE2200 family small protein	-
AB3422_RS02475 (AB3422_02475)	-	480069..480524 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3422_RS02480 (AB3422_02480)	-	480769..481530 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1026060 AB3422_RS02450 WP_000143419.1 476375..477262(-) (braS) [Staphylococcus aureus strain TUM20888]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1026060 AB3422_RS02450 WP_000143419.1 476375..477262(-) (braS) [Staphylococcus aureus strain TUM20888]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997